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Secuado vs. Latuda

 

Are Secuado and Latuda the Same Thing?

Secuado (asenapine) and Latuda (lurasidone hydrochloride) are atypical antipsychotics used to treat schizophrenia.

Secuado is available as a transdermal system (patch) and Latuda is taken orally.

Asenapine, the drug contained in Secuado, is also available as a sublingual tablet formulation under the brand name Saphris.

Side effects of Secuado and Latuda that are similar include weight gain.

Side effects of Secuado that are different from Latuda include headache, extrapyramidal disorder (muscle spasms, restlessness, muscle rigidity, slowness of movement, tremors, and irregular, jerky movements), and application site reactions (skin discoloration, discomfort, dryness, swelling, redness, peeling, hard lump, irritation, pain, bumps, or itching).

Side effects of Latuda that are different from Secuado include drowsiness, dizziness, nausea, diarrhea, stomach pain, loss of appetite, shaking, muscle stiffness, mask-like facial expression, inability to keep still, restlessness, agitation, blurred vision, breast swelling or discharge, missed menstrual periods, decreased sex drive, impotence, and difficulty having an orgasm.

Both Secuado and Latuda may interact with antibiotics and antidepressants.

Secuado may also interact with diuretics, ACE inhibitors, angiotensin receptor blockers (ARBs), beta-blockers, and alpha-blockers.

Latuda may also interact with diltiazem, azole antifungals, HIV drugs, rifamycins, and other products that cause dizziness or drowsiness (including alcohol, antihistamines, drugs for sleep or anxiety, muscle relaxants, and narcotics).

What Are Possible Side Effects of Secuado?

Side effects of Secuado include:

  • headache,
  • extrapyramidal disorder (muscle spasms, restlessness, muscle rigidity, slowness of movement, tremors, and irregular, jerky movements),
  • application site reactions (skin discoloration, discomfort, dryness, swelling, redness, peeling, hard lump, irritation, pain, bumps, or itching), and
  • weight gain

What Are Possible Side Effects of Latuda?

Common side effects of Latuda include:

  • drowsiness,
  • dizziness,
  • nausea,
  • diarrhea,
  • stomach pain,
  • loss of appetite,
  • shaking,
  • muscle stiffness,
  • weight gain,
  • mask-like facial expression,
  • inability to keep still,
  • restlessness,
  • agitation,
  • blurred vision,
  • breast swelling or discharge,
  • missed menstrual periods,
  • decreased sex drive,
  • impotence, or
  • difficulty having an orgasm.

Tell your doctor right if you experience serious side effects of Latuda including:

  • drooling,
  • trouble swallowing,
  • fainting,
  • signs of infection (such as persistent cough, fever)
  • fast or uneven or pounding heartbeats;
  • agitation, hostility, confusion, thoughts about hurting yourself,
  • seizures (convulsions),
  • fever, chills, body aches, flu symptoms,
  • sores in your mouth and throat,
  • high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss),
  • very stiff (rigid) muscles, high fever, sweating, confusion, tremors, feeling like you might pass out, or
  • twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs

What Is Secuado?

Secuado (asenapine) is a transdermal atypical antipsychotic formulation used to treat adults with schizophrenia. Asenapine, the drug contained in Secuado, is also available as a sublingual tablet formulation under the brand name Saphris.

Secuado is also used to treat or manage:

Secuado Injection is a prescription medicine used to treat:

  • agitation associated with schizophrenia or bipolar mania

It is not known if Secuado is safe or effective in children:

  • under 13 years of age with schizophrenia
  • under 10 years of age with bipolar I disorder
  • under 6 years of age with irritability associated with autistic disorder
  • under 6 years of age with Tourette's disorder

What Is Latuda?

Latuda (lurasidone hydrochloride) is an atypical antipsychotic used to treat schizophrenia.

 

What Drugs Interact With Secuado?

Secuado may interact with other medicines such as:

Tell your doctor all medications and supplements you use.

What Drugs Interact With Latuda?

Latuda may interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety), antibiotics, antifungal medications, or medications to treat HIV or AIDS.

 

How Should Secuado Be Taken?

The recommended starting dose of Secuado is 3.8 mg/24 hours. Apply one Secuado patch to the skin (hip, abdomen, upper arm, or upper back area) every 24 hours

How Should Latuda Be Taken?

The recommended starting dose of Latuda is 40 mg once dxily, and it has been shown to be effective in a dose range of 40 mg/day to 160 mg/day.