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Omnipred vs. Durezol

Are Omnipred and Durezol the Same Thing?

Omnipred (prednisolone acetate) Ophthalmic Suspension and Durezol (difuprednate) Ophthalmic Emulsion 0.05% are corticosteroids used to treat inflammation of the eye from different causes.

Omnipred is used to treat eye irritation and inflammation caused by allergies, eye infections, or any general irritation to the eye.

Durezol is used to treat eye swelling caused by surgery.

Side effects of Omnipred and Durezol that are similar include increased sensitivity of the eyes to light and stinging/burning/itching/irritation in your eyes.

Side effects of Omnipred that are different from Durezol include temporary cloudy vision, increased pressure in the eyes, glaucoma, optic nerve damage, cataracts, and delayed wound healing.

Side effects of Durezol that are different from Omnipred include temporary blurred vision, headache, dry or watery eyes, and feeling like something is in your eye.

Both Omnipred and Durezol may interact with other drugs.

What Are Possible Side Effects of Omnipred?

Common side effects of Omnipred include:

  • temporary cloudy vision,
  • increased sensitivity of the eyes to light,
  • stinging/burning/itching/irritation in your eyes,
  • increased pressure in the eyes,
  • glaucoma,
  • optic nerve damage,
  • cataracts, and
  • delayed wound healing

What Are Possible Side Effects of Durezol?

Common side effects of Durezol include:

  • temporary blurred vision,
  • headache,
  • burning/stinging/itching of your eyes,
  • dry or watery eyes,
  • feeling like something is in your eye, or
  • increased sensitivity of your eyes to light.

Use of Durezol for prolonged or repeated periods may result in a new fungal infection. Tell your doctor if you have unlikely but serious side effects of Durezol including:

  • new or increased eye pain/swelling/discharge/redness,
  • eye pain or discomfort in bright light, or
  • vision changes.

What Is Omnipred?

Omnipred (prednisolone acetate) Ophthalmic Suspension is an adrenocortical steroid is used to treat inflammation caused by allergies, eye infections, or any general irritation to the eye.

What Is Durezol?

Durezol (difuprednate) Ophthalmic Emulsion 0.05% ophthalmic (for the eye) is a topical anti-inflammatory corticosteroid used to treat eye swelling caused by surgery.

What Drugs Interact With Omnipred?

Other drugs may interact with Omnipred. Tell your doctor all medications you take. Do not stop using Omnipred suddenly. Avoid touching the bottle tip to eyelids or to any other surface. Use of the bottle by more than one person may spread the infection. If you are pregnant only use Omnipred if the potential benefit outweighs the potential risk to the fetus. Do not use Omnipred if you are breastfeeding.

What Drugs Interact With Durezol?

It is not likely other drugs you take orally or inject will have an effect on Durezol ophthalmic used in the eyes. But many drugs can interact with each other. Tell your doctor all prescription and over-the-counter medications and supplements you use. During pregnancy, Durezol should be used only when prescribed. It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.

How Should Omnipred Be Taken?

The recommended dosage of Omnipred is two drops in the eyes four times per day.

How Should Durezol Be Taken?

The dose of Durezol is one drop instilled into the conjunctival sac of the affected eye(s) 4 times daily beginning 24 hours after surgery and continuing throughout the first 2 weeks of the postoperative period, followed by 2 times daily for a week and then a taper based on the response.

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