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Definition of Heart septum

Medically reviewed by Min Clinic Staff | Updated: January 2026

Heart septum: The dividing wall between the right and left sides of the heart. That portion of the septum that separates the right and left atria of the heart is termed the atrial, or interatrial, septum, whereas the portion of the septum that lies between the right and left ventricles of the heart is called the ventricular, or interventricular, septum.