Colocort
- Generic Name: hydrocortisone rectal suspension
- Brand Name: Colocort
Colocort (Hydrocortisone Rectal Suspension) side effects drug center
Colocort Side Effects Center
What Is Colocort?
Colocort (hydrocortisone suspension) is a corticosteroid used as adjunctive therapy in the treatment of ulcerative colitis, especially distal forms, including ulcerative proctitis, ulcerative proctosigmoiditis, and left-sided ulcerative colitis. It has also proven useful in some cases involving the transverse and ascending colons.
What Are Side Effects of Colocort?
Side effects of Colocort include:
- local pain or burning,
- rectal bleeding,
- sodium retention,
- fluid retention,
- congestive heart failure in susceptible patients,
- potassium loss,
- high blood pressure (hypertension),
- muscle weakness,
- osteoporosis,
- peptic ulcer,
- abdominal distention,
- slow wound healing,
- thin fragile skin,
- facial redness,
- increased sweating,
- convulsions,
- spinning sensation (vertigo),
- headache, and
- menstrual irregularities
Dosage for Colocort
The usual course of therapy is one Colocort nightly for 21 days, or until the patient comes into remission both clinically and proctologically. Clinical symptoms usually subside promptly within 3 to 5 days. Difficult cases may require as long as 2 or 3 months of Colocort treatment.
Colocort In Children
Safety and effectiveness of Colocort in pediatric patients have not been established. Growth and development of pediatric patients on prolonged corticosteroid therapy should be carefully observed.
What Drugs, Substances, or Supplements Interact with Colocort?
Colocort may interact with other medicines such as:
- aspirin
Tell your doctor all medications and supplements you use.
Colocort During Pregnancy and Breastfeeding
Tell your doctor if you are pregnant or plan to become pregnant before using Colocort; it is unknown how it would affect a fetus. Neonates born of mothers who have received substantial doses of corticosteroids such as Colocort during pregnancy should be carefully observed for signs of hypoadrenalism. Consult your doctor before breastfeeding.
Additional Information
Our Colocort (hydrocortisone suspension) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Colocort Consumer Information
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- severe rectal pain or burning, bleeding from your rectum;
- fever or other signs of infection;
- vision changes;
- muscle weakness, joint pain, bone pain;
- unusual changes in mood or behavior;
- severe headaches, ringing in your ears, pain behind your eyes;
- a seizure;
- heart problems--chest pain, irregular heartbeats, swelling, rapid weight gain;
- low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling;
- low calcium level--muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes); or
- signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.
Common side effects may include:
- stomach pain, bloating;
- acne, rash, redness, dryness;
- changes in your menstrual periods;
- increased sweating; or
- changes in the shape or location of body fat (especially in your face, neck and waist).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Colocort (Hydrocortisone Rectal Suspension)
Colocort Professional Information
SIDE EFFECTS
Local pain or burning, and rectal bleeding attributed to hydrocortisone rectal suspension have been reported rarely. Apparent exacerbations or sensitivity reactions also occur rarely. The following adverse reactions should be kept in mind whenever corticosteroids are given by rectal administration.
Fluid And Electrolyte Disturbances
Sodium retention; fluid retention; congestive heart failure in susceptible patients; potassium loss; hypokalemic alkalosis; hypertension.
Musculoskeletal: Muscle weakness; steroid myopathy; loss of muscle mass; osteoporosis; vertebral compression fractures; asceptic necrosis of femoral and humeral heads; pathologic fracture of long bones.
Gastrointestinal: Peptic ulcer with possible perforation and hemorrhage; pancreatitis; abdominal distention; ulcerative esophagitis.
Dermatologic: Impaired wound healing; thin fragile skin; petechiae and ecchymoses; facial erythema; increased sweating; may suppress reactions to skin tests.
Neurological: Convulsions; increased intracranial pressure with papilledema (pseudo-tumor cerebri) usually after treatment; vertigo; headache.
Endocrine: Menstrual irregularities; development of Cushingoid state; suppression of growth in pediatric patients; secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery or illness, decreased carbohydrate tolerance; manifestations of latent diabetes requirements for insulin or oral hypoglycemic agents in diabetics.
Ophthalmic: Posterior subcapsular cataracts; increased intraocular pressure; glaucoma; exophthalmos.
Metabolic: Negative nitrogen balance due to protein catabolism.
Read the entire FDA prescribing information for Colocort (Hydrocortisone Rectal Suspension)
© Colocort Patient Information is supplied by Cerner Multum, Inc. and Colocort Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.