Winuron: Full Drug Profile
Winuron - General Information
Winuron is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Winuron is known to be effective against penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of parenteral administration seen with penicillin, especially anaphylactic shock.
Pharmacology of Winuron
Winuron is a nonfluorinated quinolone antibiotic. Its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Winuron is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.
Additional information about Winuron
- Winuron Indication
For the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients.
- Mechanism Of Action
- Winuron binds to and inhibits the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, repair, and recombination.
- Generic Name
- Rosoxacin
- Synonyms
- ROS; Rosoxacino [Inn-Spanish]; Rosoxacine [Inn-French]; Acrosoxacin
- Drug Category
- Anti-Infective Agents
- Drug Type
- Small Molecule; Approved
- Other Brand Names containing Rosoxacin
- Eracine; Eradacil; Eradacin; Roxadyl; Winuron;
- Chemical IUPAC Name
- 1-ethyl-4-oxo-7-pyridin-4-ylquinoline-3-carboxylic acid
- Chemical Formula
- C17H14N2O3
- Organisms Affected
- Enteric bacteria and other eubacteria
