Vipicil

Vipicil - General Information

A cyclohexylamido analog of penicillanic acid. [PubChem]

Pharmacology of Vipicil

Vipicil, a penicillin, is a cyclohexylamido analog of penicillanic acid. Vipicil is more resistant to beta-lactamase hydrolysis than ampicillin, is much better absorbed when given by mouth and, as a result, the levels reached in the blood and in the urine are considerably higher than those obtained with the same dose of ampicillin. Vipicil has been replaced by newer penicillin treatments.

Additional information about Vipicil

Vipicil Indication: For the treatment of bacterial infections caused by susceptible organisms.
Mechanism Of Action: The bactericidal activity of cyclacillin results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Vipicil is stable in the presence of a variety of b-lactamases, including penicillinases and some cephalosporinases.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Cyclacillin
Synonyms: Ciclacilline [INN-French]; Ciclacillinum [INN-Latin]; Ciclacilina [INN-Spanish]; Aminocyclohexylpenicillin; Ciclacillin; Ciclacillum
Drug Category: Anti-Bacterial Agents
Drug Type: Small Molecule; Approved

Other Brand Names containing Cyclacillin: Bastcillin; Calthor; Citosarin; Cyclapen; Cyclapen-W; Orfilina; Syngacillin; Ultracillin; Vastcillin; Vipicil; Wyvital;
Absorption: Moderately absorbed.
Toxicity (Overdose): Symptoms of overdose include severe diarrhea, nausea and vomiting.
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Vipicil: Not Available
Chemical IUPAC Name: (2S,5R,6R)-6-[(1-aminocyclohexanecarbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Chemical Formula: C15H23N3O4S
Cyclacillin on Wikipedia: Not Available
Organisms Affected: Enteric bacteria and other eubacteria