Vercyte: Full Drug Profile
Vercyte - General Information
An antineoplastic agent that acts by alkylation. [PubChem]
Pharmacology of Vercyte
Vercyte is an antineoplastic agent. Specifically it is a piperazine derivative with a chemical structure close to that of many DNA alkylating agents. Vercyte has well documented clinical activity against polycythemia vera and essential thrombocythemia.
Vercyte for patients
Vercyte Interactions
Vercyte Contraindications
Children under 15 years of age. Lactation. Bone marrow depression due to chemotherapy or X rays.
Additional information about Vercyte
Vercyte Indication: For the treatment of polycythaemia vera and refractory chronic myeloid leukaemia. Mechanism Of Action: The mechanism of action is uncertain but pipobroman is thought to alkylate DNA leading to disruption of DNA synthesis and eventual cell death. Drug Interactions: Acebutolol AntagonismAtenolol AntagonismBetaxolol AntagonismBevantolol AntagonismBisoprolol AntagonismCarteolol AntagonismCarvedilol AntagonismEsmolol AntagonismLabetalol AntagonismMetoprolol AntagonismNadolol AntagonismOxprenolol AntagonismPenbutolol AntagonismPindolol AntagonismPractolol AntagonismPropranolol AntagonismSotalol AntagonismTimolol Antagonism Food Interactions: Not Available Generic Name: Pipobroman Synonyms: Not Available Drug Category: Antineoplastic Agents Drug Type: Small Molecule; Approved Other Brand Names containing Pipobroman: Amedel; Vercyte; Absorption: Well absorbed from the GI tract. Toxicity (Overdose): Symptoms of overdose include hematologic toxicity, especially with chronic overdosage. Protein Binding: Not Available Biotransformation: Not Available Half Life: Not Available Dosage Forms of Vercyte: Not Available Chemical IUPAC Name: 3-bromo-1-[4-(3-bromopropanoyl)piperazin-1-yl]propan-1-one Chemical Formula: C10H16Br2N2O2 Pipobroman on Wikipedia: https://en.wikipedia.org/wiki/Pipobroman Organisms Affected: Humans and other mammals