Transbilix: Full Drug Profile

Transbilix - General Information

A water-soluble radiographic contrast media for cholecystography and intravenous cholangiography. [PubChem]

Pharmacology of Transbilix

Not Available

Additional information about Transbilix

Transbilix Indication

Used as a contrast agent for cholecystography and intravenous cholangiography.

Mechanism Of Action

Organic iodine compounds block x-rays as they pass through the body, thereby allowing body structures containing iodine to be delineated in contrast to those structures that do not contain iodine. The degree of opacity produced by these iodinated organic compounds is directly proportional to the total amount (concentration and volume) of the iodinated contrast agent in the path of the x-rays. Transbilix's primary excretion through the hepato-biliary system and concentration in bile allows visualization of the gallbladder and biliary ducts.

Generic Name

Iodipamide

Synonyms

3,3'-[(1,6-dioxohexane-1,6-diyl)diimino]bis(2,4,6-triiodobenzoic acid); Iodipamic acid; Adipiodone; Adipiodonum [INN-Latin]; Adipiodona [INN-Spanish]; IDB

Drug Category

Contrast Media

Drug Type

Small Molecule; Approved

Other Brand Names containing Iodipamide

Transbilix; Cholospect; Cholografin; Biligrafin; Bilignostum; Bilignost;

Toxicity (Overdose)

Acute IV LD50 is 5000 mg/kg in rat, 3195 mg/kg in mouse, and 1200 mg/kg in dog.

Biotransformation

Hepatic.

Dosage Forms of Transbilix

Injection, solution Intravenous drip

Chemical IUPAC Name

3-[[6-[(3-carboxy-2,4,6-triiodophenyl)amino]-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid

Chemical Formula

C20H14I6N2O6

Organisms Affected

Humans and other mammals