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Tao: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Tao - General Information

A macrolide antibiotic that is similar to erythromycin.

 

Pharmacology of Tao

Tao is a macrolide antibiotic that is similar to erythromycin. It is active in vitro against the following gram-positive organisms: Streptococcus pyogenes and Diplococcus pneumoniae.

 

Tao for patients

 

Tao Interactions

 

Tao Contraindications

Troleandomycin is contraindicated in patients with known hypersensitivity to this antibiotic.

 

Additional information about Tao

Tao Indication: For the treatment of Pneumococcal pneumonia due to susceptible strains and group A beta-hemolytic streptococcal infections of the upper respiratory tract. Mechanism Of Action: Tao acts by penetrating the bacterial cell membrane and reversibly binding to the 50 S subunit of bacterial ribosomes or near the "P" or donor site so that binding of tRNA (transfer RNA) to the donor site is blocked. Translocation of peptides from the "A" or acceptor site to the "P" or donor site is prevented, and subsequent protein synthesis is inhibited. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Troleandomycin Synonyms: Triacetyloleandomycin; Oleandomycin triacetate; Oleandomycin, triacetate (ester); Oleandomycin triacetyl ester; Oleandocetine Drug Category: Antibacterial Agents; Macrolides Drug Type: Small Molecule; Approved Other Brand Names containing Troleandomycin: Cyclamycin; Evramicina; Matromicina; Tao; Treolmicina; Tribiocillina; Absorption: Not Available Toxicity (Overdose): Symptoms of overdose include diarrhea, nausea, stomach cramps, and vomiting. Protein Binding: Not Available Biotransformation: Not Available Half Life: Not Available Dosage Forms of Tao: Capsule Oral Chemical IUPAC Name: [(3R,5S,6S,7R,8S,9R,12R,13S,14S,15R)-6-[(2S,3R,4S,6R)-3-acetyloxy-4-dimethylamino-6-methyloxan-2-yl]oxy-8-[(2R,4S,5S,6S)-5-acetyloxy-4-methoxy-6-methyloxan-2-yl]oxy-5,7,9,12,13,15-hexamethyl-10,16-dioxo-1,11-dioxaspiro[2.13]hexadecan-14-yl] acetate Chemical Formula: C41H67NO15 Troleandomycin on Wikipedia: https://en.wikipedia.org/wiki/Troleandomycin Organisms Affected: Enteric bacteria and other eubacteria