Succitimal

Succitimal - General Information

Succitimal is an anticonvulsant in the succinimide class. It suppresses the paroxysmal three cycle per second spike and wave EEG pattern associated with lapses of consciousness in petit mal seizures. The frequency of attacks is reduced by depression of nerve transmission in the motor cortex.

Pharmacology of Succitimal

Succitimal suppresses the paroxysmal three cycle per second spike and wave EEG pattern associated with lapses of consciousness in absence (petit mal) seizures. The frequency of attacks is reduced by depression of nerve transmission in the motor cortex.

Succitimal for patients

Succitimal Interactions

Succitimal Contraindications

Contraindications

- hypersensitivity to succinimides.

- Use cautiously with hepatic, renal abnormalities, acute intermittent porphyria, pregnancy (association between use of antiepileptic drugs by women with epilepsy and an elevated incidence of birth defects in children born to these women; however, antiepileptic therapy should not be discontinued in pregnant women who are receiving such therapy to prevent major seizures; the effect of even minor seizures on the developing fetus is unknown, and this should be considered when deciding whether to continue antiepileptic therapy in pregnant women), lactation.

Additional information about Succitimal

Succitimal Indication: For the treatment of epilepsy
Mechanism Of Action: Succitimal's mechanism of action not understood, but may act in inhibitory neuronal systems that are important in the generation of the three per second rhythm
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Phensuximide
Synonyms: Not Available
Drug Category: Anticonvulsants; Antiepileptic Agents
Drug Type: Small Molecule; Approved

Other Brand Names containing Phensuximide: (+/-)-N-Methyl-2-phenylsuccinimide; 1-Methyl-3-Phenylsuccinimide; Epimid; Fenosuccimide; Fensuccimide [DCIT]; Fensuximida [INN-Spanish]; Lifene; Methylphenylsuccinimide; Milontin; Milontin (TN); Milonton; Mirontin; Mirotin; 7 Phenosuccimide; N-Methyl-2-phenylsuccinimide; N-Methyl-alpha-phenolsuccinimide; N-Methyl-alpha-phenylsuccinimide; Phensuximid; Phensuximide (USP); Phensuximide [BAN-INN]; Phensuximidum [INN-Latin]; Phenylsuximide; Succinimide, N-methyl-2-phenyl-; Succitimal;
Absorption: Rapid and complete
Toxicity (Overdose): Not Available
Protein Binding: 21%
Biotransformation: Hepatic
Half Life: Not Available
Dosage Forms of Succitimal: Not Available
Chemical IUPAC Name: 1-methyl-3-phenylpyrrolidine-2,5-dione
Chemical Formula: C11H11NO2
Phensuximide on Wikipedia: https://en.wikipedia.org/wiki/Phensuximide
Organisms Affected: Humans and other mammals