Star GLA (GNC)
Star GLA (GNC) - General Information
A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5. [PubChem]
Pharmacology of Star GLA (GNC)
Dihomo gamma-linolenic acid or DHLA is an n-6 (omega-6) polyunsaturated fatty acid. It is comprised of 20 carbon atoms and three double bonds. DHLA is a byproduct of the 18 carbon gamma-linolenic acid (GLA). DHLA is then converted into prostaglandin E1 (PGE1). PGE1 inhibits platelet aggregation and also exerts a vasodilatory effect.
Additional information about Star GLA (GNC)
Star GLA (GNC) Indication: For nutritional supplementation, also for treating dietary shortage or imbalance
Mechanism Of Action: DHLA (or DGLA) is a precursor in the synthesis of prostaglandin E1 (PGE1) as well as the series-3 prostaglandins. It also serves as a precursor in the synthesis of eicosapentaenoic acid (EPA). EPA is a precursor of the series-3 prostaglandins, the series-5 leukotrienes and the series-3 thromboxanes. These eicosanoids have anti-thrombogenic, anti-inflammatory and anti-atherogenic properties. PGE1 inhibits platelet aggregation and has a vasodilation action. DHLA has also been shown to reduce the production/activity of tumor necrosis factor alpha.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: gamma-Homolinolenic acid
Synonyms: (8E,11E,14E)-8,11,14-Icosatrienoic acid; 8,11,14-Eicosatrienoic Acid; (Z,Z,Z)-8,11,14-Eicosatrienoic acid; cis-8,11,14-Eicosatrienoic acid; DGLA; Dihomo-gamma-linolenic acid; Homo-gamma-linolenic acid
Drug Category: Dietary supplement; Micronutrient
Drug Type: Small Molecule; Nutraceutical; Approved
Other Brand Names containing gamma-Homolinolenic acid: Tona-lean 1000 CLA (Action Labs); Star GLA (GNC);
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Star GLA (GNC): Capsule Oral
Chemical IUPAC Name: (8Z,11Z,14Z)-icosa-8,11,14-trienoic acid
Chemical Formula: C20H34O2
gamma-Homolinolenic acid on Wikipedia: Not Available
Organisms Affected: Humans and other mammals
