Speed
Speed - General Information
Speed is a psychostimulant and sympathomimetic drug. It is a member of the amphetamine group of sympathomimetic amines and is a scheduled drug in most countries.
Pharmacology of Speed
Speed is a potent central nervous system stimulant which affects neurochemical mechanisms responsible for regulating heart rate, body temperature, blood pressure, appetite, attention, mood and responses associated with alertness or alarm conditions. The acute effects of the drug closely resemble the physiological and psychological effects of an epinephrine-provoked fight-or-flight response, including increased heart rate and blood pressure, vasoconstriction (constriction of the arterial walls), bronchodilation, and hyperglycemia (increased blood sugar). Users experience an increase in focus, increased mental alertness, and the elimination of fatigue, as well as a decrease in appetite.
Additional information about Speed
Speed Indication: For the treatment of Attention Deficit Disorder with Hyperactivity (ADHD) and exogenous obesity.
Mechanism Of Action: Speed enters the brain and triggers a cascading release of norepinephrine, dopamine and serotonin. To a lesser extent methamphetamine acts as a dopaminergic and adrenergic reuptake inhibitor and in high concentrations as a monamine oxidase inhibitor (MAOI). The mechanism of action involved in producing the beneficial behavioral changes seen in hyperkinetic children receiving methamphetamine is unknown.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Methamphetamine
Synonyms: (+ )-methylamphetamine; (+)-(s)-deoxyephedrine; (+)-(s)-n-alpha-dimethylphenethylamine; (+)-2-(N-Methylamino)-1-phenylpropane; (+)-methamphetamine; (+)-methylamphetamine; (+)-n,alpha-dimethyl-beta-phenylethylamine; (+)-n,alpha-dimethylphenethylamine; (+)-n-methylamphetamine; (2S)-N-methyl-1-phenylpropan-2-amine; (s)-(+)-deoxyephedrine; (s)-(+)-methamphetamine; (s)-(+)-n,alpha,dimethylphenethylamine; (s)-methamphetamine; (s)-methylamphetamine; (s)-n,alpha-dimethylbenzeneethanamine; (s)-n,alpha-dimethylbenzeneethanoamine; 1-Phenyl-2-methylamino-propan [German]; 1-Phenyl-2-methylaminopropane; 2S-(+)-Methamphetamine; D-(s)-methamphetamine; D-1-Phenyl-2-methylaminopropane; d-1-Phenyl-2-methylaminopropan [German]; D-deoxyephedrine; D-methylamphetamine; D-methamphetamine; D-desoxyephedrine; D-n,alpha-dimethylphenethylamine; D-n-methylamphetamine; D-phenylisopropylmethylamine; Desoxyephedrine hydrochloride; L-methamphetamine; Metamfetamina [inn-spanish]; Metamfetaminum [inn-latin]; Metamphetamine; Metanfetamina [inn-spanish]; Methamphetaminum [inn-latin]; Methyl-beta-phenylisopropylamine; Methylamphetamine; N-Methyl-1-phenyl-2-propanamine; N-methyl-beta-phenylisopropylamin [german]; N-methyl-beta-phenylisopropylamine; N-methylamphetamine; S-(+)-methamphetamine; Ice; Meth
Drug Category: Adrenergic Agents; Adrenergic Uptake Inhibitors; Central Nervous System Stimulants; Dopamine Agents; Dopamine Uptake Inhibitors; Sympathomimetics
Drug Type: Small Molecule; Illicit; Approved
Other Brand Names containing Methamphetamine: Desoxyn; Desyphed; Desyphed hydrochloride; Metamfetamine; Metamfetamine-m; Norodin; Speed; Stimulex;
Absorption: Rapidly absorbed from the gastrointestinal tract.
Toxicity (Overdose): Manifestations of acute overdosage with methamphetamine include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, panic states, hyperpyrexia, and rhabdomyolysis. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include arrhythmias, hypertension or hypotension, and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea, and abdominal cramps. Fatal poisoning usually terminates in convulsions and coma.
Protein Binding: Not Available
Biotransformation: Hepatic. The primary site of metabolism is in the liver by aromatic hydroxylation, N-dealkylation and deamination. At least seven metabolites have been identified in the urine.
Half Life: The biological half-life has been reported in the range of 4 to 5 hours.
Dosage Forms of Speed: Tablet Oral
Chemical IUPAC Name: (2S)-N-methyl-1-phenylpropan-2-amine
Chemical Formula: C10H15N
Methamphetamine on Wikipedia: https://en.wikipedia.org/wiki/Methamphetamine
Organisms Affected: Humans and other mammals
