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Spasmoban: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Spasmoban - General Information

A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms. [PubChem]

 

Pharmacology of Spasmoban

Spasmoban is an anticholinergic drug, a medication that reduces the effect of acetylcholine, a chemical released from nerves that stimulates muscles, by blocking the receptors for acetylcholine on smooth muscle (a type of muscle). It also has a direct relaxing effect on smooth muscle. Spasmoban is used to treat or prevent spasm in the muscles of the gastrointestinal tract in the irritable bowel syndrome. In addition, Spasmoban inhibits gastrointestinal propulsive motility and decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretions.

 

Spasmoban for patients

Dicyclomine may produce drowsiness or blurred vision. The patient should be warned not to engage in activities requiring mental alertness, such as operating a motor vehicle or other machinery or to perform hazardous work while taking this drug.

Dicyclomine is contraindicated in infants less than 6 months of age and in nursing mothers..

In the presence of a high environmental temperature, heat prostration can occur with drug use (fever and heat stroke due to decreased sweating).

If symptoms occur the drug should be discontinued and a physician contacted.

 

Spasmoban Interactions

The following agents may increase certain actions or side effects of anticholinergic drugs. amantadine antiarrhythmic agents of class (e.g. quinidine), antihistamines antipsychotic agents (e.g. phenothiazines), benzodiazepines. MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity.

Anticholinergics antagonize the effects of antiglaucoma agents. Anticholinergic drugs in the presence of increased intraocular pressure may be hazardous when taken concurrently with agents such as corti costeroids..

Anticholinergic agents may affect gastrointestinal absorption of various drugs, such as slowly dissolving dosage forms of digoxin; increased serum digoxin concentrations may result.

Anticholinergic drugs may antagonize the effects of the drugs that alter gastrointestinal motility, such as metoclopramide. Because antacids may interfere with the absorption of anticholinergic agents, simultaneous use of these drugs should be avoided.

The inhibiting effects of anticholinergic drugs on gastric hydrochloric acid secretion are antagonized by agents used to treat achlorhydria and those used to test gastric secretion.

 

Spasmoban Contraindications

1. Obstructive uropathy
2. Obstructive disease of the gastrointestinal tract
3. Severe ulcerative colitis
4. Reflux esophagitis
5. Unstable cardiovascular status in acute hemorrhage
6. Glaucoma
7. Myasthenia gravis
8. Evidence of prior hypersensitivity to dicyclomine hydrochloride or other ingredients of these formulations
9. Infants less than 6 months of age
10. Nursing Mothers

 

Additional information about Spasmoban

Spasmoban Indication: For the treatment of functional bowel/irritable bowel syndromeincluding Colicky abdominal pain; diverticulitis Mechanism Of Action: Action is achieved via a dual mechanism: (1) a specific anticholinergic effect (antimuscarinic) at the acetylcholine-receptor sites and (2) a direct effect upon smooth muscle (musculotropic). Drug Interactions: Donepezil Possible antagonism of actionGalantamine Possible antagonism of actionRivastigmine Possible antagonism of actionHaloperidol The anticholinergic increases the risk of psychosis and tardive dyskinesia Food Interactions: Avoid alcohol.Take this medication 30 minutes before meals. Generic Name: Dicyclomine Synonyms: Not Available Drug Category: Anticholinergic Agents; Antispasmodics; Antimuscarinics Drug Type: Small Molecule; Approved Other Brand Names containing Dicyclomine: Atumin; Bentomine; Bentyl; Bentyl Hydrochloride; Bentylol; Bentylol Hydrochloride; Di-Syntramine; Dicicloverina [Inn-Spanish]; Dicyclomine Hcl; Dicyclomine Hydrochloride; Dicycloverin; Dicycloverin Hydrochloride; Dicycloverine; Dicycloverine Hydrochloride; Dicycloverinum [Inn-Latin]; Diethylaminocarbethoxybicyclohexyl Hydrochloride; Diocyl; Diocyl Hydrochloride; Dyspas; Formulex; Kolantyl Hydrochloride; Mamiesan; Merbentyl; Oxityl-P; Procyclomin; Sawamin; Spasmoban; Wyovin; Wyovin Hydrochloride; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: >99% Biotransformation: Not Available Half Life: Not Available Dosage Forms of Spasmoban: Tablet OralCapsule OralSolution IntramuscularSyrup Oral Chemical IUPAC Name: 2-diethylaminoethyl 1-cyclohexylcyclohexane-1-carboxylate Chemical Formula: C19H35NO2 Dicyclomine on Wikipedia: https://en.wikipedia.org/wiki/Dicyclomine Organisms Affected: Humans and other mammals