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Rigenox: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Rigenox - General Information

A hypnotic and sedative. Its use has been largely superseded by other drugs. [PubChem]

 

Pharmacology of Rigenox

Rigenox is a hypnotic sedative that was introduced in 1954 as a safe alternative to barbiturates to treat insomnia. Before long, however, it had become clear that glutethimide was just as likely to cause addiction and caused similarly severe withdrawal symptoms.

 

Additional information about Rigenox

Rigenox Indication: For the treatment of insomnia. Mechanism Of Action: Not Available Drug Interactions: Anisindione The agent decreases the anticoagulant effectDicumarol The agent decreases the anticoagulant effectAcenocoumarol The agent decreases the anticoagulant effectWarfarin The agent decreases the anticoagulant effectDonepezil Possible antagonism of actionGalantamine Possible antagonism of actionRivastigmine Possible antagonism of action Food Interactions: Take without regard to meals.Avoid alcohol. Generic Name: Glutethimide Synonyms: Gluthetimide; Glutathimid; Glutethimid; Glutetimid; Glutetimide Drug Category: Hypnotics and Sedatives Drug Type: Small Molecule; Illicit; Approved Other Brand Names containing Glutethimide: Sarodormin; Doriden; Elrodorm; Alfimid; Noxiron; Noxyron; Ondasil; Rigenox; Glimid; Gimid; Absorption: Variable Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Hepatic. Glutethimide is almost completely metabolized. Half Life: 10-12 hours Dosage Forms of Rigenox: Not Available Chemical IUPAC Name: 3-ethyl-3-phenylpiperidine-2,6-dione Chemical Formula: C13H15NO2 Glutethimide on Wikipedia: https://en.wikipedia.org/wiki/Glutethimide Organisms Affected: Humans and other mammals