Medical Information Only: This medication is not sold on this site. The information provided is for reference purposes only. Please consult your local physician or pharmacist for treatment.

Raniclor: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Raniclor - General Information

Semisynthetic, broad-spectrum antibiotic derivative of cephalexin. [PubChem]

 

Pharmacology of Raniclor

Raniclor is a second generation cephalosporin antibiotic with a spectrum resembling first-generation cephalosporins. In vitro tests demonstrate that the bactericidal action of the cephalosporins results from inhibition of cell-wall synthesis. Raniclor has been shown to be active against most strains of the following microorganisms, both in vitro and in clinical infections: Gram positive aerobes - Staphylococci (including coagulase-positive, coagulase-negative, and penicillinase-producing strains), Streptococcus pneumoniae, and Streptococcus pyogenes (group A ß-hemolytic streptococci). Gram-negative aerobes - Escherichia coli, Haemophilus influenzae (including ß-lactamase-producing ampicillin-resistant strains), Klebsiella sp, and Proteus mirabilis.

 

Raniclor for patients

Patients should be counseled that antibacterial drugs including Ceclor should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). When Ceclor is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Ceclor or other antibacterial drugs in the future.

 

Raniclor Interactions

No information provided.

 

Raniclor Contraindications

Cefaclor is contraindicated in patients with known allergy to the cephalosporin group of antibiotics.

 

Additional information about Raniclor

Raniclor Indication

For the treatment of certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.

Mechanism Of Action
Raniclor, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins. It is possible that cefaclor interferes with an autolysin inhibitor.
Drug Interactions
Probenecid Probenecid increases the antibiotic's level
Food Interactions
Preferably on an empty stomach, not really problematic.
Generic Name
Cefaclor
Synonyms
CCL; Cefaclor anhydrous; Cefaclorum [INN-Latin]; Cephaclor
Drug Category
Anti-Bacterial Agents; Cephalosporins
Drug Type
Small Molecule; Approved
Other Brand Names containing Cefaclor
Alenfral; Alfacet; Alfatil; Ceclor; Ceclor CD; Distaclor; Kefral; Panacef; Panoral; Raniclor;
Absorption
Well absorbed after oral administration, independent of food intake.
Toxicity (Overdose)
Symptoms of overdose include diarrhea, nausea, stomach upset, and vomiting.
Protein Binding
23.5%
Biotransformation
No appreciable biotransformation in liver (approximately 60% to 85% of the drug is excreted unchanged in the urine within 8 hours).
Half Life
0.6-0.9 hour
Dosage Forms of Raniclor
Powder, for solution Oral
Chemical IUPAC Name
(6R,7R)-7-[(2-amino-2-phenylacetyl)amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Chemical Formula
C15H14ClN3O4S
Organisms Affected
Enteric bacteria and other eubacteria