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Proformiphen: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Proformiphen - General Information

3,6-Diaminoacridine. Topical antiseptic used mainly in wound dressings. [PubChem]

 

Pharmacology of Proformiphen

Proformiphen is an acriflavine derivative which is a disinfectant bacteriostatic against many gram-positive bacteria. Proformiphen is toxic and carcinogenic in mammals and so it is used only as a surface disinfectant or for treating superficial wounds.

 

Additional information about Proformiphen

Proformiphen Indication: Topical antiseptic used mainly in wound dressings. Mechanism Of Action: Proformiphen acts by interchelating DNA (intercalation), thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands. This prevents bacterial reproduction. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Proflavine Synonyms: Not Available Drug Category: Anti-Infectives, local Drug Type: Small Molecule; Approved Other Brand Names containing Proflavine: Isoflav Base; Pro-Gen; Proflavin; Profoliol-B; Proformiphen; Profura; Progarmed; Progesic; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Not Available Half Life: Not Available Dosage Forms of Proformiphen: Not Available Chemical IUPAC Name: acridine-3,6-diamine Chemical Formula: C13H11N3 Proflavine on Wikipedia: https://en.wikipedia.org/wiki/Proflavine Organisms Affected: Enteric bacteria and other eubacteria