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Patanol: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Patanol - General Information

Used to treat allergic conjunctivitis (itching eyes), olopatadine inhibits the release of histamine from mast cells. It is a relatively selective histamine H1 antagonist that inhibits the in vivo and in vitro type 1 immediate hypersensitivity reaction including inhibition of histamine induced effects on human conjunctival epithelial cells.

 

Pharmacology of Patanol

Used to treat allergic conjunctivitis (itching eyes), olopatadine inhibits the release of histamine from mast cells. It is a relatively selective histamine H1 antagonist that inhibits the in vivo and in vitro type 1 immediate hypersensitivity reaction including inhibition of histamine induced effects on human conjunctival epithelial cells.

 

Patanol for patients

 

Patanol Interactions

No information provided.

 

Patanol Contraindications

PATANOL (olopatadine hydrochloride ophthalmic solution) 0.1% is contraindicated in persons with a known hypersensitivity to olopatadine hydrochloride or any components of PATANOL.

 

Additional information about Patanol

Patanol Indication

For the treatment of the signs and symptoms of allergic conjunctivitis.

Mechanism Of Action
Patanol is a selective histamine H1 antagonist and binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. Patanol is devoid of effects on alpha-adrenergic, dopamine and muscarinic type 1 and 2 receptors.
Generic Name
Olopatadine
Drug Category
Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihistamines; Histamine H1 Antagonists
Drug Type
Small Molecule; Approved
Other Brand Names containing Olopatadine
Olopatadine Hydrochloride; Patanol;
Absorption
Ophthalmic use of olopatadine usually does not produce measurable plasma concentrations.
Biotransformation
The mono-desmethyl and the N-oxide metabolites have been detected at low concentrations in the urine.
Half Life
3 hours
Dosage Forms of Patanol
Liquid Ophthalmic
Chemical IUPAC Name
2-[(11Z)-11-(3-dimethylaminopropylidene)-6H-benzo[c][2]benzoxepin-2-yl]acetic acid
Chemical Formula
C21H23NO3
Organisms Affected
Humans and other mammals