Medical Information Only: This medication is not sold on this site. The information provided is for reference purposes only. Please consult your local physician or pharmacist for treatment.

Not Available: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Not Available - General Information

Not Available is a folic acid derivative. It is produced from dihydrofolic acid by dihydrofolate reductase.
It is converted into 5,10-methylenetetrahydrofolate by serine hydroxymethyltransferase. It is a coenzyme in many reactions, especially in the metabolism of amino acids and nucleic acids. It acts as a donor of a group with one carbon atom. It gets this carbon atom by sequestering formaldehyde produced in other processes.

 

Pharmacology of Not Available

Tetrahydrofolate is the main active metabolite of dietary folate. It is vital as a coenzyme in reactions involving transfers of single carbon groups. Tetrahydrofolate has a role in nucleic and amino acid synthesis. As nucleic and amino acid synthesis is affected by a deficiency of tetrahydrofolate, actively dividing and growing cells tend to be the first affected. Tetrahydrofolate is used to treat topical sprue and megaloblastic and macrocytic anemias, hematologic complications resulting from a deficiency in folic acid.

 

Additional information about Not Available

Not Available Indication: For nutritional supplementation, also for treating dietary shortage or imbalance. Mechanism Of Action: Tetrahydrofolate is transported across cells by receptor-mediated endocytosis where it is needed to maintain normal erythropoiesis, synthesize purine and thymidylate nucleic acids, interconvert amino acids, methylate tRNA, and generate and use formate. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Tetrahydrofolic acid Synonyms: tetrahydropteroylglutamate; tetrahydropteroyl mono-L-glutamate; tetrahydrafolate; tetra-H-folate; tetrahydrofolate; N-(4-(((2-Amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)glutamic acid; H4PteGlu; th-folate; THF; folate-H4; FH4; 5,6,7,8-tetrahydrofolic acid; 5,6,7,8-tetrahydrofolate; (6S)-tetrahydrofolate Drug Category: Dietary supplement; Micronutrient Drug Type: Small Molecule; Nutraceutical; Approved Other Brand Names containing Tetrahydrofolic acid: Not Available; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Not Available Half Life: Not Available Dosage Forms of Not Available: Not Available Chemical IUPAC Name: (2S)-2-[[4-[(2-amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid Chemical Formula: C19H23N7O6 Tetrahydrofolic acid on Wikipedia: https://en.wikipedia.org/wiki/Tetrahydrofolic_acid Organisms Affected: Humans and other mammals