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Medrocort: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Medrocort - General Information

Medrocort is a corticosteroid used in ophthalmology. [Wikipedia]

 

Pharmacology of Medrocort

Medrocort is a topical anti-inflammatory corticoidsteroids for ophthalmic use. In patients with increased intraocular pressure and in those susceptible to a rise in intraocular pressure, there is less effect on pressure with medrysone than with dexamethasone or betamethasone. Corticoidsteroids inhibit the edema, fibrin deposition, capillary dilation, and phagocytic migration of the acute inflammatory response, as well as capillary proliferation, deposition of collagen, and scar formation.

 

Medrocort for patients

 

Medrocort Interactions

No Informatuion Provided.

 

Medrocort Contraindications

HMS® (medrysone) is contraindicated in the following conditions:

Acute superficial herpes simplex

Viral diseases of the conjunctiva and cornea

Ocular tuberculosis

Fungal diseases of the eye

Hypersensitivity to any of the components of the drug

 

Additional information about Medrocort

Medrocort Indication: For the treatment of allergic conjunctivitis, vernal conjunctivitis, episcleritis, and epinephrine sensitivity. Mechanism Of Action: There is no generally accepted explanation for the mechanism of action of ocular corticosteroids. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Medrysone Synonyms: Hydroxymesterone Drug Category: Topical anti-inflammatory Agent Drug Type: Small Molecule; Approved Other Brand Names containing Medrysone: HMS Liquifilm; Medrifar; Medritonic; Medrocort; Visudrisone; HMS; Absorption: Rapidly absorbed following oral administration. Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Not Available Half Life: Not Available Dosage Forms of Medrocort: Solution / drops Ophthalmic Chemical IUPAC Name: (6S,8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-6,10,13-trimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one Chemical Formula: C22H32O3 Medrysone on Wikipedia: https://en.wikipedia.org/wiki/Medrysone Organisms Affected: Humans and other mammals