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Landruma: Full Drug Profile
Medically reviewed by Min Clinic Staff | Updated: January 2026
Landruma - General Information
An analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis. [PubChem]
Pharmacology of Landruma
Niflumic acid, a nonsteroidal anti-inflammatory fenamate, is a Ca2+-activated Cl- channel blocker.
Additional information about Landruma
- Landruma Indication
Used in the treatment of rheumatoid arthritis.
- Generic Name
- Niflumic Acid
- Synonyms
- 2-[(3-Trifluoromethyl)Phenyl]Amino-3-Pyridine-Carboxylic Acid; Niflumate; Nifluminic acid; NFL; NFA; Lopac-N-0630; Acidum niflumicum [inn-latin]; Acido niflumico [inn-spanish]; Acide niflumique [inn-french]; 2-[3-(Trifluoromethyl)anilino]nicotinic acid; 2-(alpha,alpha,alpha-Trifluoro-m-toluidino)nicotinic acid; 2-(3-Trifluoromethyl-phenylamino)-nicotinic acid; 2-(3-(Trifluoromethyl)anilino)nicotinic acid; 2-(3-(Trifluoromethyl)-phenyl)aminonicotinic acid
- Drug Category
- Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors
- Drug Type
- Small Molecule; Approved
- Other Brand Names containing Niflumic Acid
- Actol; Niflam; Nifluril; Landruma; Forenol; Flogovital;
- Absorption
- Well absorbed following oral administration.
- Toxicity (Overdose)
- Oral, mouse: LD50 = 350 mg/kg; Oral, rat: LD50 = 250 mg/kg
- Protein Binding
- 90% bound to plasma proteins.
- Biotransformation
- Hepatic.
- Half Life
- 2.5 hours
- Chemical IUPAC Name
- 2-[[3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylic acid
- Chemical Formula
- C13H9F3N2O2
- Organisms Affected
- Humans and other mammals