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Humatin: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Humatin - General Information

An oligosaccharide antibiotic produced by various streptomyces. [PubChem]

 

Pharmacology of Humatin

Humatin is a broad spectrum antibiotic produced by Streptomyces rimosus var. paromomycinus. The in vitro and in vivo antibacterial action of paromomycin closely parallels that of neomycin.

 

Humatin for patients

 

Humatin Interactions

 

Humatin Contraindications

Paromomycin sulfate is contraindicated in individuals with a history of previous hypersensitivity reactions to it. It is also contraindicated in intestinal obstruction.

 

Additional information about Humatin

Humatin Indication: For the treatment of acute and chronic intestinal amebiasis (it is not effective in extraintestinal amebiasis). Also for the management of hepatic coma as adjunctive therapy. Mechanism Of Action: Humatin inhibits protein synthesis by binding to 16S ribosomal RNA. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Paromomycin Synonyms: Aminosidin; Aminosidine; Paramomycin sulfate Drug Category: Antibacterial Agents Drug Type: Small Molecule; Approved; Investigational Other Brand Names containing Paromomycin: Humatin; Absorption: Poorly absorbed after oral administration, with almost 100% of the drug recoverable in the stool. Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Not Available Half Life: Not Available Dosage Forms of Humatin: Capsule OralCapsule Oral Chemical IUPAC Name: (2R,3S,4R,5R,6S)-5-amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxy-2-(hydroxymethyl)oxane-3,4-diol Chemical Formula: C23H45N5O14 Paromomycin on Wikipedia: https://en.wikipedia.org/wiki/Paromomycin_sulfate Organisms Affected: Enteric bacteria and other eubacteria