Hazol

Hazol - General Information

A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251)

Pharmacology of Hazol

Hazol a adrenergic alpha-agonists, direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion The sympathomimetic action of oxymetazoline constricts the smaller arterioles of the nasal passages, producing a prolonged (up to 12 hours), gentle and decongesting effect. Hazol elicits relief of conjunctival hyperemia by causing vasoconstriction of superficial conjunctival blood vessels. The drug's action has been demonstrated in acute allergic conjunctivitis and in chemical (chloride) conjunctivitis.

Additional information about Hazol

Hazol Indication: For treatment of nasal congestion and redness associated with minor irritations of the eye
Mechanism Of Action: Hazol is a direct acting sympathomimetic amine, which acts on alpha-adrenergic receptors in the arterioles of the conjunctiva and nasal mucosa. It produces vasoconstriction, resulting in decreased conjunctival congestion in ophthalmic. In nasal it produces constriction, resulting in decreased blood flow and decreased nasal congestion.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Oxymetazoline
Synonyms: oxymetazoline hydrochloride crystalline; Oxymethazoline; Oxymetozoline; Oximetazolinum
Drug Category: Adrenergic alpha-Agonists; Nasal Decongestants; Sympathomimetics
Drug Type: Small Molecule; Approved

Other Brand Names containing Oxymetazoline: Afrin; Afrin Cherry 12 Hour Nasal Spray; Afrin Extra Moisturizing 12 Hour Nasal Spray; Afrin Original 12 Hour Nasal Spray; Afrin Original 12 Hour Nose Drops; Afrin Original 12 Hour Pump Mist; Afrin Sinus 12 Hour Nasal Spray; Dristan Long Lasting Mentholated Nasal Spray; Dristan Long Lasting Nasal Mist; Drixoral Nasal Solution; Duramist Plus Up To 12 Hour Nasal Decongestant Spray; Duration 12 Hour Nasal Spray; Genasal Nasal Spray Up to 12 Hour Relief; Hazol; Iliadin; Nafrine; Nasal Relief 12 Hour Nasal Spray; Nasivine; Navasin; Navisin; Neo-Synephrine 12 Hour Spray; Nezeril; Nostrilla 12 Hour Nasal Decongestant; OcuClear; Oxylazine; Rhinofrenol; Rhinolitan; Sinerol; Vicks Sinex 12 Hour Nasal Spray; Vicks Sinex 12 Hour Ultra Fine Mist for Sinus Relief; Visine L.R; Visine L.R.;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Hazol: Solution Nasal
Solution / drops Ophthalmic
Spray Nasal
Liquid Nasal
Solution Respiratory (inhalation)
Chemical IUPAC Name: 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
Chemical Formula: C16H24N2O
Oxymetazoline on Wikipedia: https://en.wikipedia.org/wiki/Oxymetazoline
Organisms Affected: Humans and other mammals