Medical Information Only: This medication is not sold on this site. The information provided is for reference purposes only. Please consult your local physician or pharmacist for treatment.

Epogen (Amgen Inc.): Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Epogen (Amgen Inc.) - General Information

Human erythropoietin (recombinant), produced by CHO cells.

 

Pharmacology of Epogen (Amgen Inc.)

Used in the treatment of anemia. Involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.

 

Epogen (Amgen Inc.) for patients

 

Epogen (Amgen Inc.) Interactions

No evidence of interaction of PROCRIT with other drugs was observed in the course of clinical trials. 

 

Epogen (Amgen Inc.) Contraindications

PROCRIT is contraindicated in patients with:  

1. Uncontrolled hypertension

2. Known hypersensitivity to mammalian cell-derived products

3. Known hypersensitivity to Albumin (Human)

 

Additional information about Epogen (Amgen Inc.)

Epogen (Amgen Inc.) Indication: For treatment of anemia (from renal transplants or certain HIV treatment) Mechanism Of Action: Binding of erythropoietin to the erythropoietin receptor leads to receptor dimerization, which facilitates activation of JAK-STAT signaling pathways within the cytosol. Activated STAT (signal transducers and activators of transcription) proteins are then translocated to the nucleus where they serve as transcription factors which regulate the activation of specific genes involved in cell division or differentiation. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Epoetin alfa Synonyms: Epoetin; Erythropoietin precursor Drug Category: Antianemic Agents Drug Type: Biotech; Approved Other Brand Names containing Epoetin alfa: Epogen (Amgen Inc.); Epogin (Chugai); Epomax (Elanex); Eprex (Janssen-Cilag. Ortho Biologics LLC); NeoRecormon (Roche); Procrit (Ortho Biotech); Recormon (Roche); Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Not Available Half Life: Not Available Dosage Forms of Epogen (Amgen Inc.): Liquid SubcutaneousSolution SubcutaneousSolution Intravenous Chemical IUPAC Name: Human erythropoietin Chemical Formula: C815H1317N233O241S5 Epoetin alfa on Wikipedia: https://en.wikipedia.org/wiki/Epoetin_alfa Organisms Affected: Humans and other mammals