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Emcyt: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Emcyt - General Information

A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties. [PubChem]

 

Pharmacology of Emcyt

Emcyt is an antineoplastic agent indicated in the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate. Emcyt is a combination of estradiol with nornitrogen mustard. The precise mechanism of action of estramustine is unknown. Unlike other alkylating agents, estramustine does not directly damage DNA.

 

Emcyt for patients

 

Emcyt Interactions

Milk, milk products, and calcium-rich foods or drugs may impair the absorption of EMCYT.

 

Emcyt Contraindications

EMCYT Capsules should not be used in patients with any of the following conditions:

  1. Known hypersensitivity to either estradiol or to nitrogen mustard.
  2. Active thrombophlebitis or thromboembolic disorders, except in those cases where the actual tumor mass is the cause of the thromboembolic phenomenon and the physician feels the benefits of therapy may outweigh the risks.

 

Additional information about Emcyt

Emcyt Indication: For the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate Mechanism Of Action: The precise mechanism of action of estramustine is unknown. Drug Interactions: Clodronate Clodronate increases the levels of estramustine Food Interactions: Take on an empty stomach.Do not take with milk or milk products. Generic Name: Estramustine Synonyms: Estramustinum [Inn-Latin]; Estramustine Sodium Phosphate; Estramustina [Inn-Spanish]; Estramustin Sodium Phosphate Drug Category: Antineoplastic Agents; Radiation-Protective Agents Drug Type: Small Molecule; Approved Other Brand Names containing Estramustine: Emcyt; Estracyt; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Not Available Half Life: 20 hours Dosage Forms of Emcyt: Capsule Oral Chemical IUPAC Name: (17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl) N,N-bis(2-chloroethyl)carbamate Chemical Formula: C23H31Cl2NO3 Estramustine on Wikipedia: https://en.wikipedia.org/wiki/Estramustine Organisms Affected: Humans and other mammals