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E-Complex-600: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

E-Complex-600 - General Information

A generic descriptor for all tocopherols and tocotrienols that exhibit alpha-tocopherol activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of isoprenoids. [PubChem]

 

Pharmacology of E-Complex-600

E-Complex-600 has antioxidant activity. It may also have anti-atherogenic, antithrombotic, anticoagulant, neuroprotective, antiviral, immunomodulatory, cell membrane-stabilizing and antiproliferative actions. E-Complex-600 is a collective term used to describe eight separate forms, the best-known form being alpha-tocopherol. E-Complex-600 is a fat-soluble vitamin and is an important antioxidant. It acts to protect cells against the effects of free radicals, which are potentially damaging by-products of the body's metabolism. E-Complex-600 is often used in skin creams and lotions because it is believed to play a role in encouraging skin healing and reducing scarring after injuries such as burns. There are three specific situations when a vitamin E deficiency is likely to occur. It is seen in persons who cannot absorb dietary fat, has been found in premature, very low birth weight infants (birth weights less than 1500 grams, or 3½ pounds), and is seen in individuals with rare disorders of fat metabolism. A vitamin E deficiency is usually characterized by neurological problems due to poor nerve conduction. Symptoms may include infertility, neuromuscular impairment, menstrual problems, miscarriage and uterine degradation. Preliminary research has led to a widely held belief that vitamin E may help prevent or delay coronary heart disease. Antioxidants such as vitamin E help protect against the damaging effects of free radicals, which may contribute to the development of chronic diseases such as cancer. It also protects other fat-soluble vitamins (A and B group vitamins) from destruction by oxygen. Low levels of vitamin E have been linked to increased incidence of breast and colon cancer.

 

E-Complex-600 for patients

  • Take with or after meals.
  • Solution may be dropped in mouth or mixed with food.
  • Store in a tight, light-resistant container.

 

E-Complex-600 Interactions

  • Increased action of oral anticoagulants.
  • Decreased absorption of colestipol, cholestyramine, mineral oil, and sucralfate.

 

E-Complex-600 Contraindications

Contraindicated in those sensitive to vitamin E.

 

Additional information about E-Complex-600

E-Complex-600 Indication

E-Complex-600, known for its antioxidant activities, is protective against cardiovascular disease and some forms of cancer and has also demonstrated immune-enhancing effects. It may be of limited benefit in some with asthma and rheumatoid arthritis. It may be helpful in some neurological diseases including Alzheimer's, some eye disorders including cataracts, and diabetes and premenstrual syndrome. It may also help protect skin from ultraviolet irradiation although claims that it reverses skin aging, enhances male fertility and exercise performance are poorly supported. It may help relieve some muscle cramps.

Mechanism Of Action
Although all forms of E-Complex-600 exhibit antioxidant activity, it is known that the antioxidant activity of vitamin E is not sufficient to explain the vitamin's biological activity.
Generic Name
Vitamin E
Synonyms
alpha-Tocopherol; Tocopherol
Drug Category
Dietary supplement; Micronutrient; Antioxidants; Vitamins/minerals
Drug Type
Small Molecule; Nutraceutical; Approved
Other Brand Names containing Vitamin E
Amino-Opti-E; Aquasol E; Daltose; E-200 I.U. Softgels; E-Complex-600; E-Ferol; E-Vitamin succinate; Gordo-Vite E; Vitamin Plus E Softgells; Vitec;
Absorption
50 to 80% absorbed from gastrointestinal tract.
Protein Binding
Bound to beta-lipoproteins in blood.
Biotransformation
Hepatic.
Dosage Forms of E-Complex-600
Tablet Oral
Chemical IUPAC Name
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-ol
Chemical Formula
C29H50O2
Organisms Affected
Humans and other mammals