Dosing and uses of Cipro HC Otic (hydrocortisone-ciprofloxacin)
Adult dosage forms and strengths
ciprofloxacin/hydrocortisone
suspension
- 0.2%/1%
Acute Otitis Externa
3 gtt in affected ear q12hr for 7 days
Pediatric dosage forms and strengths
ciprofloxacin/hydrocortisone
suspension
- 0.2%/1%
Acute Otitis Externa
< 1 year
- Safety and efficacy not established
> 1 year
- 3 gtt in affected ear q12hr for 7 days
Cipro HC Otic (hydrocortisone-ciprofloxacin) adverse (side) effects
Frequency not defined
Headache
Pruritus
Migraine headache
Hyperesthesia
Paresthesias
Fungal dermatitis
Cough
Rash
Dermatitis
Urticaria
Alopecia
Warnings
Contraindications
Hypersensitivity to drugs or components
Tympanic membrane perforation (nonsterile preparation)
Viral infections of external canal including varicella & herpes simplex infections
Cautions
Prolonged use may result in bacterial or fungal overgrowth
Resistance to the product may develop
Pregnancy and lactation
Pregnancy category: C
Lactation: Excretion in breast milk unknown; not recommended
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Cipro HC Otic (hydrocortisone-ciprofloxacin)
Mechanism of action
Ciprofloxacin: Fluoroquinolone antibiotic; inhibits DNA gyrase; promotes breakage of double-stranded DNA; bactericidaL
Hydrocortisone: Antiinflammatory agent
