Gotu Kola (brahmabuti, centella asiatica, hydrocotyle, Indian pennywort, Indian water navelwort, madescassol, marsh penny, talepetrako, thick-leaved pennywort, white rot)
Classes: Dermatology, Herbals; Neurology & Psychiatry, Herbals
Suggested dosing of Brahmabuti, centella asiatica (gotu kola)
Extract
60mg PO BID-TId
Dried leaves
600 mg PO TId
Tea
1 cup PO TID; 600 mg dried leaves/150 ml water
Other Information
Topical: apply 1% cream daily
Suggested uses of Brahmabuti, centella asiatica (gotu kola)
Abdominal disorders, aphrodisiac, common cold/flu, fatigue, memory enhancer, varicose veins, venous insufficiency
Topical: hypertrophic scarring, psoriasis, wound healing
Efficacy
Possibly effective for listed uses
Brahmabuti, centella asiatica (gotu kola) adverse (side) effects
Frequency not defined
GI upset
Nausea
Photosensitivity
Pruritis
Topical: Allergic contact dermatitis
Burning
Large dose: Drowsiness
Hypercholesterolemia
Hyperglycemia
Hypertension
Hypertriglyceridemia
Sedation
Warnings
Contraindications
None reported
Cautions
Concurrent sedative agents, diabetes mellitus, hyperlipidemia
Pregnancy and lactation
Pregnancy category: avoid use
Lactation: avoid use
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Brahmabuti, centella asiatica (gotu kola)
Metabolism: N/A
Excretion: N/A
Mechanism of action
Triterpene compounds stimulate connective tissue repair, keratinization
Asiaticoside derivatives protect neurons from beta-amyloid toxicity
