Aloe (aloe vera, Aloe arborescens natalenis, Aloe barbadensis, Aloe ferox, Aloe vulgari)

Suggested dosing of aloe vera, Aloe arborescens natalenis (aloe)

 

Leaf gel cap

50-200 mg/day PO

 

Liquid

30 ml PO TId

 

Tincture

15-60 gtts PO PRN; 1:10, 50% alcohoL

 

Topical

Apply 3-5 qDay PRn

 

Suggested uses of aloe vera, Aloe arborescens natalenis (aloe)

Promote wound healing

Anesthesia, antiseptic, arthritis, burns, cold sores, fever, inflammation, moisturizer, pruritis

 

Efficacy

Possibly effective for pain, inflammation, wound healing

 

aloe vera, Aloe arborescens natalenis (aloe) adverse (side) effects

Frequency not defined

Hypoglycemia

 

Warnings

Contraindications

None reported

 

Cautions

Abdominal discomfort (PO use), appendicitis (PO use), Crohn's disease (PO use), diabetes mellitus, hemorrhoids (PO use), intestinal obstruction (PO use), kidney disease (PO use), nausea/vomiting (PO use), PUD (PO use), ulcerative colitis (PO use)

 

Pregnancy and lactation

Pregnancy category: N/A

Lactation: N/A

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of aloe vera, Aloe arborescens natalenis (aloe)

Metabolism: N/A

Excretion: N/A

 

Mechanism of action

Carboxypeptidase, salicylate inhibit bradykinin

Magnesium lactate inhibits histamine