Aloe (aloe vera, Aloe arborescens natalenis, Aloe barbadensis, Aloe ferox, Aloe vulgari)
Classes: Dermatology, Herbals
Suggested dosing of aloe vera, Aloe arborescens natalenis (aloe)
Leaf gel cap
50-200 mg/day PO
Liquid
30 ml PO TId
Tincture
15-60 gtts PO PRN; 1:10, 50% alcohoL
Topical
Apply 3-5 qDay PRn
Suggested uses of aloe vera, Aloe arborescens natalenis (aloe)
Promote wound healing
Anesthesia, antiseptic, arthritis, burns, cold sores, fever, inflammation, moisturizer, pruritis
Efficacy
Possibly effective for pain, inflammation, wound healing
aloe vera, Aloe arborescens natalenis (aloe) adverse (side) effects
Frequency not defined
Hypoglycemia
Warnings
Contraindications
None reported
Cautions
Abdominal discomfort (PO use), appendicitis (PO use), Crohn's disease (PO use), diabetes mellitus, hemorrhoids (PO use), intestinal obstruction (PO use), kidney disease (PO use), nausea/vomiting (PO use), PUD (PO use), ulcerative colitis (PO use)
Pregnancy and lactation
Pregnancy category: N/A
Lactation: N/A
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of aloe vera, Aloe arborescens natalenis (aloe)
Metabolism: N/A
Excretion: N/A
Mechanism of action
Carboxypeptidase, salicylate inhibit bradykinin
Magnesium lactate inhibits histamine