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Nocdurna: Detailed Datasheet

Medically reviewed by Min Clinic Staff | Updated: January 2026
  • Generic Name: desmopressin acetate sublingual tablets
  • Brand Name: Nocdurna

side effects drug center nocdurna (desmopressin acetate sublingual tablets) drug - patient side effects and images

 

PROFESSIONAL

CONSUMER

SIDE EFFECTS

Nocdurna Patient Information Including Side Effects

Brand Names: DDAVP, Nocdurna

Generic Name: desmopressin (oral/sublingual)

What is desmopressin (DDAVP, Nocdurna)?

Desmopressin is used to treat nighttime bed-wetting, central diabetes insipidus, and increased thirst and urination caused by head surgery or head trauma.

Desmopressin is a man-made form of a hormone that occurs naturally in the pituitary gland and regulates how the body uses water.

Desmopressin may also be used for purposes not listed in this medication guide.

What are the possible side effects of desmopressin (DDAVP, Nocdurna)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

Serious side effects may be more likely in older adults.

Common side effects may include:

  • headache;
  • dizziness;
  • dry mouth;
  • nausea; or
  • mild stomach pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about desmopressin (DDAVP, Nocdurna)?

You should not use desmopressin if you have severe kidney disease or hyponatremia (low sodium levels in your body). You also should not take Nocdurna if you have severe thirst, uncontrolled hypertension, heart failure, high levels of a hormone that causes fluid retention, or if you take a diuretic or use steroid medication.

Limit your intake of water and other fluids while you are using desmopressin. Drinking too much water may lead to a serious, life-threatening electrolyte imbalance.

Call your doctor right away if you have signs of low sodium: headache, confusion, muscle cramps, severe weakness, vomiting, loss of coordination, and feeling restless or unsteady.

Nocdurna Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking desmopressin (DDAVP, Nocdurna)?

You should not use desmopressin if you are allergic to it, or if you have:

  • severe kidney disease; or
  • hyponatremia (low sodium levels in your body).

You also should not take Nocdurna sublingual desmopressin if you have:

  • a disease or psychologic disorder that causes extreme or unusual thirst;