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Effexor XR Side Effects Center

Medically reviewed by Min Clinic Staff | Updated: January 2026

Effexor XR(Venlafaxine Hydrochloride Extended-Release) side effects drug center

 

PROFESSIONAL

CONSUMER

SIDE EFFECTS

 

Effexor Xr Side Effects Center

What Is Effexor Xr?

Effexor XR (venlafaxine hydrochloride extended-release) is an antidepressant used to treat patients with major depressive disorders such as panic and social disorders. Effexor XR is available as a generic.

What Are Side Effects of Effexor XR?

Common side effects of Effexor XR include:

  • nausea,
  • constipation,
  • insomnia,
  • dizziness,
  • asthenia,
  • drowsiness,
  • dry mouth,
  • nervousness,
  • strange dreams,
  • blurred vision,
  • changes in appetite or weight,
  • decreased sex drive,
  • impotence,
  • difficulty having an orgasm, and
  • increased sweating.

Tell your doctor if you have unlikely but serious side effects of Effexor XR including:

  • easy bruising or bleeding,
  • decreased interest in sex,
  • changes in sexual ability,