Diamox vs. Mannitol

• Are Diamox and Mannitol the Same Thing?
• What Are Possible Side Effects of Diamox?
• What Are Possible Side Effects of Mannitol?
• What is Diamox?
• What is Mannitol?
• What Drugs Interact with Diamox?
• What Drugs Interact with Mannitol?
• How Should Diamox Be Taken?
• How Should Mannitol Be Taken?

Diamox Sequels (acetazolamide) and Mannitol (mannitol injection) are used to treat glaucoma.

Diamox Sequels is also used to treat and to prevent acute mountain sickness (altitude sickness). Diamox Sequels is also used as a part of some treatment plans for congestive heart failure and seizure disorders.

Mannitol is also used to increase urine production, and to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, kidney failure).

Common side effects of Diamox include:

• dizziness,
• lightheadedness, and
• an increased amount of urine, especially during the first few days as your body adjusts to the medication.

Other side effects of Diamox Sequels include:

• blurred vision or changes in vision,
• dry mouth,
• drowsiness,
• loss of appetite,
• stomach upset,
• nausea,
• vomiting,
• constipation,
• diarrhea,
• changes in taste,
• headache,
• tiredness,
• drowsiness,
• fatigue,
• weakness,
• nervousness,
• mild tremor,
• confusion,
• increased sensitivity of the skin to sunlight,
• worsening gout,
• loss of blood sugar control (if you are diabetic), or
• ringing in your ears or hearing problems.

Tell your doctor if you have unlikely but serious side effects of Diamox Sequels including:

• increased body hair,
• hearing loss,
• unusual tiredness,
• persistent nausea or vomiting, or
• severe stomach or abdominal pain.

Common side effects of Mannitol include:

• headache,
• nausea,
• diarrhea,
• vomiting,
• dry mouth,
• thirst,
• dehydration,
• blurred vision,
• nausea,
• vomiting,
• runny nose,
• arm pain,
• chills,
• dizziness,
• low blood pressure (hypotension),
• hives,
• irregular heart beat,
• electrolyte imbalance, and
• irritation/pain/swelling at the injection site.

Diamox Sequels (acetazolamide) is a carbonic anhydrase inhibitor used to treat glaucoma and to treat and to prevent acute mountain sickness (altitude sickness). Diamox Sequels is also used as a part of some treatment plans for congestive heart failure and seizure disorders.

Mannitol I.V. (mannitol injection) is a diuretic used to increase urine production, and to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure).

Diamox Sequels may interact with cyclosporine, primidone, diflunisal, aspirin and other salicylates, or lithium. Tell your doctor all medications you use. Diamox Sequels should be used during pregnancy only if prescribed. This medication passes into breast milk but is unlikely to harm a nursing infant.

Mannitol may interact with other drugs. Tell your doctor all medications and supplements you use.

To treat glaucoma, the recommended dosage of Diamox Sequels is 1 capsule (500 mg) two times a day. To treat acute mountain sickness, dosage is 500 mg to 1000 mg daily, in divided doses using tablets or extended-release capsules as appropriate.

The usual adult dosage of Mannitol ranges from 50 to 200 g in a 24-hour period, but in most instances an adequate response will be achieved at a dosage of approximately 100 g/24 hours.