Goldenseal

Goldenseal suggested uses include for the common cold, conjunctivitis, diarrhea, dysmenorrhea/menorrhagia, flatulence, gastritis/colitis, mouth/gum sores, respiratory infections, ringworm, urinary tract infections, and urine drug tests.

• Goldenseal is available under the following different brand and other names: berberine, eye balm, eye root, goldenroot, ground raspberry, Hydrastis canadensis, Indian plant, jaundice root, orange root, and yellow root.

Suggested Dosing

Dried Root/Rhizome/Tea

• 0.5-1 g orally three times daily

Liquid Extract

• 0.3-1.0 ml orally three times daily; 1:1, 60% ethanol

Tincture

• 2-4 ml orally three times daily; 1:10, 60% ethanol

Mouthwash, Topical

• Rinse three to four times daily; with 6 g dried herb/150 ml water

Dosage Considerations – Should be Given as Follows:

• See "Suggested Dosing"

Common side effects of goldenseal include:

• Excitability
• Hallucinations
• Constipation
• Delirium
• Digestive disorders
• Kernicterus (pediatric)
• Irritation of the mouth, throat, or vagina
• Skin irritation
• Increased sensitivity to sunlight

Side effects of goldenseal overdose (OD) include:

• Cardiac damage
• Death
• Depression
• Low blood pressure (hypotension)
• Nausea/vomiting
• Nervousness
• Paralysis
• Respiratory failure
• Seizures
• Shortness of breath
• Slow heart rate
• Spasms

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

• Goldenseal has no known severe, serious, moderate, or mild interactions with other drugs.

This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.

This medication contains goldenseal. Do not take berberine, eye balm, eye root, goldenroot, ground raspberry, Hydrastis canadensis, Indian plant, jaundice root, orange root, or yellow root if you are allergic to goldenseal or any ingredients contained in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

• Breastfeeding, hyperbilirubinemia, infectious gastrointestinal (GI) conditions, inflammatory GI conditions, newborn/infant, pregnancy

Effects of Drug Abuse

• Side effects of goldenseal overdose (OD) include cardiac damage, death, depression, low blood pressure (hypotension), nausea/vomiting, nervousness, paralysis, respiratory failure, seizures, shortness of breath, slow heart rate, or spasms.

Short-Term Effects

• See "What Are Side Effects Associated with Using Goldenseal?"

Long-Term Effects

• See "What Are Side Effects Associated with Using Goldenseal?"

Cautions

• Cardiovascular disorders, concurrent antihypertensives, concurrent CYP 3A4 substrates, concurrent sedative agents, high blood pressure (hypertension)

Pregnancy and Lactation

• Do not use goldenseal in pregnancy. The risks involved outweigh the potential benefits. Safer alternatives exist.
• Goldenseal is unsafe to use while breastfeeding.