Latanoprost

Latanoprost is a prostaglandin analogue ophthalmic solution used to treat pressure in the eye (glaucoma, ocular hypertension) by decreasing liquid in the eye.

Latanoprost is available under the following different brand names: Xalatan.

Dosage Forms and Strengths

0.005%

Dosage Considerations – Should be Given as Follows:

1 drop in affected eye once/day in evening

Other Indications and Uses

Open-angle glaucoma

Pediatric: Safety and efficacy not established

Common side effects of latanoprost include:

• Increase in brown pigmentation of the iris
• Blurred vision
• Burning/stinging/itching/redness of the eye after using the drops
• Foreign body sensation/ feeling as if something is in the eye
• Punctate epithelial keratopathy
• Conjunctival hyperemia
• Upper respiratory tract infection/cold/flu
• Dry eyes
• Excessive tearing/watery eyes
• Eye pain
• Eyelid crusting
• Eyelid swelling
• Eyelid redness
• Eyelid discomfort/pain
• Eyelid skin darkening 
• Eye pain when exposed to light (photophobia)
• Chest pain (angina pectoris)
• Muscle/joint/back pain
• Rash/allergic skin reactions
• Changes in eyelash number/color/length/thickness
• Cold or flu-like symptoms (stuffy nose, sneezing, sore throat)

Serious side effects of latanoprost include:

• Oozing or eye discharge
• Chest pain
• Vision changes
• Light sensitivity
• Redness, swelling, itching or pain in the eye

Less common side effects of latanoprost include:

• Pink eye (conjunctivitis)
• Double vision

Other side effects of latanoprost include:

• Dizziness
• Headache

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Latanoprost has no known severe interactions with other drugs.

Serious interactions of latanoprost include:

• bimatoprost

Moderate interactions of latanoprost include: ·  bromfenac ophthalmic

• diclofenac ophthalmic
• flurbiprofen ophthalmic
• ketorolac ophthalmic
• nepafenac ophthalmic
• travoprost ophthalmic

Latanoprost has no known mild interactions with other drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

Warnings

This medication contains latanoprost. Do not take Xalatan if you are allergic to latanoprost or any ingredients contained in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

Contraindications

Hypersensitivity to lantanoprost, benzalkonium chloride or other components of product

Effects of Drug Abuse

No information available

Short-Term Effects

Do not give at late evening; may cause insomnia.

May impair ability to drive and/or operate heavy machinery.

• See "What Are Side Effects Associated with Using Latanoprost?"

Long-Term Effects

Administration of amphetamine for prolonged periods of time may lead to drug dependence and must be avoided.

• See "What Are Side Effects Associated with Using Latanoprost?"

Cautions

None

Pregnancy and Lactation

Use latanoprost with caution during pregnancy if benefits outweigh risks. Animal studies show risk and human studies are not available or neither animal nor human studies were done.

It is not known whether latanoprost is distributed into milk; use with caution if breastfeeding.