Ocrevus vs. Extavia

• Are Ocrevus and Extavia the Same Thing?
• What Are Possible Side Effects of Ocrevus?
• What Are Possible Side Effects of Extavia?
• What Is Ocrevus?
• What Is Extavia?
• What Drugs Interact with Ocrevus?
• What Drugs Interact with Extavia?
• How Should Ocrevus Be Taken?
• How Should Extavia Be Taken?

Ocrevus (ocrelizumab) injection and Extavia (interferon beta-1b) Kit are used to treat relapsing forms of multiple sclerosis (MS).

Ocrevus is also used to treat primary progressive forms of multiple sclerosis (MS).

Ocrevus Extavia belong to different drug classes. Ocrevus is a CD20-directed cytolytic antibody and Extavia is made from human proteins.

Side effects of Ocrevus that are different from Extavia include upper and lower respiratory tract infections, infusion reactions (itching, rash, hives, redness, bronchospasm, swollen and sore throat, mouth pain, shortness of breath, flushing, hypotension, fever, fatigue, headache, dizziness, nausea, and fast heart rate), skin infections, depression, back pain, and pain in the extremities.

Side effects of Extavia that are different from Ocrevus include headache, muscle pain or weakness, sleep problems (insomnia), stomach or abdominal pain, swelling in your hands or feet, skin rash, hives, itching, irregular menstrual periods, flu-like symptoms (chills, fever, feeling unwell), increased sweating, decreased white blood cell count, injection site reactions (bruising, swelling, redness, pain, warm feeling, or leaking of fluid), stuffy nose, and irregular heartbeats.

Ocrevus may interact with other immune-modulating or immunosuppressive therapies, including immunosuppressant doses of corticosteroids.

Extavia may interact with alcohol and other drugs.

Common side effects of Ocrevus include:

• upper respiratory tract infections,
• infusion reactions (itching, rash, hives, redness, bronchospasm, swollen and sore throat, mouth pain, shortness of breath, flushing, hypotension, fever, fatigue, headache, dizziness, nausea, and fast heart rate),
• skin infections,
• lower respiratory tract infections,
• depression,
• back pain, and
• pain in the extremities.

Common side effects of Extavia include:

• headache,
• muscle pain or weakness,
• sleep problems (insomnia),
• stomach or abdominal pain,
• swelling in your hands or feet,
• skin rash,
• hives,
• itching,
• irregular menstrual periods,
• flu-like symptoms (chills, fever, general feeling of being unwell),
• increased sweating,
• decreased white blood cell count,
• injection site reactions (bruising, swelling, redness, pain, warm feeling, or leaking of fluid),
• stuffy nose, or
• irregular heartbeat

Ocrevus (ocrelizumab) injection is aCD20-directed cytolytic antibody indicated for the treatment of patients with relapsing or primary progressive forms of multiple sclerosis.

Extavia (interferon beta-1b) Kit is made from human proteins and is used to treat relapsing multiple sclerosis (MS). Extavia will not cure MS, it will only decrease the frequency of relapse symptoms.

Ocrevus may interact with other immune-modulating or immunosuppressive therapies, including immunosuppressant doses of corticosteroids. Tell your doctor all medications and supplements you use.

Tell your doctor all medications and supplements you use. Do not use Extavia if you are pregnant. It may be harmful to a fetus, or may cause a miscarriage. Tell your doctor if you become pregnant during treatment. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Hepatitis B virus screening is required before the first dose of Ocrevus. Pre-medicate with methylprednisolone (or an equivalent corticosteroid) and an antihistamine prior to each infusion. The starting dose of Ocrevus is 300 mg intravenous infusion, followed two weeks later by a second 300 mg intravenous infusion. Subsequent doses of Ocrevus are 600 mg intravenous infusion every 6 months.

The recommended dose of Extavia is 0.25 mg injected subcutaneously every other day. Extavia may interact with other drugs.