Mayzent vs. Extavia

• Are Mayzent and Extavia the Same Thing?
• What Are Possible Side Effects of Mayzent?
• What Are Possible Side Effects of Extavia?
• What Is Mayzent?
• What Is Extavia?
• What Drugs Interact with Mayzent?
• What Drugs Interact with Extavia?
• How Should Mayzent Be Taken?
• How Should Extavia Be Taken?

Mayzent (siponimod) and Extavia (interferon beta-1b) Kit are used to treat relapsing forms of multiple sclerosis (MS).

Extavia will not cure MS, it will only decrease the frequency of relapse symptoms.

Mayzent and Extavia belong to different drug classes. Mayzent is a sphingosine 1-phosphate receptor modulator and Extavia is a beta interferon made from human proteins.

Side effects of Mayzent and Extavia that are similar include headache.

Side effects of Mayzent that are different from Extavia include high blood pressure (hypertension), increased liver transaminase, falls, pain and swelling in extremities, nausea, dizziness, diarrhea, and slow heart rate.

Side effects of Extavia that are different from Mayzent include muscle pain or weakness, sleep problems (insomnia), stomach or abdominal pain, swelling in your hands or feet, skin rash, hives, itching, irregular menstrual periods, flu-like symptoms (chills, fever, general feeling of being unwell), increased sweating, decreased white blood cell count, injection site reactions (bruising, swelling, redness, pain, warm feeling, or leaking of fluid), stuffy nose, and irregular heartbeat.

Mayzent may interact with “live” vaccines, cancer medications, immune-modulating drugs, immunosuppressive therapies, anti-arrhythmics, QT prolonging drugs, calcium channel blockers, other drugs that may decrease heart rate, beta-blockers, fluconazole, rifampin, carbamazepine, modafinil, or efavirenz.

Extavia may interact with alcohol.

Common side effects of Mayzent include:

• headache,
• high blood pressure (hypertension),
• increased transaminase,
• falls,
• swelling of extremities,
• nausea,
• dizziness,
• diarrhea,
• slow heart rate, and
• pain in extremities

Common side effects of Extavia include:

• headache,
• muscle pain or weakness,
• sleep problems (insomnia),
• stomach or abdominal pain,
• swelling in your hands or feet,
• skin rash,
• hives,
• itching,
• irregular menstrual periods,
• flu-like symptoms (chills, fever, general feeling of being unwell),
• increased sweating,
• decreased white blood cell count,
• injection site reactions (bruising, swelling, redness, pain, warm feeling, or leaking of fluid),
• stuffy nose, or
• irregular heartbeat

Mayzent (siponimod) is a sphingosine 1-phosphate receptor modulator indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

Extavia (interferon beta-1b) Kit is made from human proteins and is used to treat relapsing multiple sclerosis (MS). Extavia will not cure MS, it will only decrease the frequency of relapse symptoms.

Mayzent may interact with:

• "live" vaccines,
• cancer medications,
• immune-modulating drugs,
• immunosuppressive therapies,
• anti-arrhythmics,
• QT prolonging drugs,
• calcium channel blockers,
• other drugs that may decrease heart rate,
• beta-blockers,
• fluconazole,
• rifampin,
• carbamazepine,
• modafinil, or
• efavirenz.

Tell your doctor all medications and supplements you use. Do not use Extavia if you are pregnant. It may be harmful to a fetus, or may cause a miscarriage. Tell your doctor if you become pregnant during treatment. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Initiate Mayzent with a 5-day titration. The recommended maintenance dosage of Mayzent is 2 mg.

The recommended dose of Extavia is 0.25 mg injected subcutaneously every other day. Extavia may interact with other drugs.