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Gantanol vs. Silvadene

Are Gantanol and Silvadene the Same Thing?

Gantanol (sulfamethoxazole) and Silvadene Cream 1% (silver sulfadiazine) are antibiotics used to treat different types of bacterial infections.

  • Gantanol is used to treat urinary tract infections (UTIs), meningitis, ear infections, and eye infections.
  • Silvadene Cream 1% is a topical (for the skin) antibiotic used to treat or prevent infections on areas of burned skin.
  • The brand name Gantanol is discontinued, but generic versions may be available.
  • Gantanol and Silvadene are different types of antibiotics. Gantanol is an antibacterial sulfonamide (a “sulfa” drug) and Silvadene is a topical (for the skin) antibiotic.
  • Side effects of Gantanol and Silvadene that are similar include upset stomach.
  • Side effects of Gantanol that are different from Silvadene include dizziness, headache, lethargy, diarrhea, weight loss, loss of appetite, nausea, vomiting, and rash.
  • Side effects of Silvadene that are different from Gantanol include pain, burning, or itching of the treated skin, and discoloration (brown/gray/blue) of skin and mucous membranes (such as the gums).
  • Gantanol may interact with diuretics, anticoagulants, phenytoin, and methotrexate.
  • Silvadene may interact with cimetidine.

What Are Possible Side Effects of Gantanol?

Common side effects of Gantanol (sulfamethoxazole) include:

What Are Possible Side Effects of Silvadene?

Common side effects of Silvadene Cream include:

  • pain,
  • burning, or
  • itching of the treated skin,
  • upset stomach, or
  • discoloration (brown/gray/blue) of skin and mucous membranes (such as the gums).

What Is Gantanol?

Gantanol (sulfamethoxazole) is an antibacterial sulfonamide used to treat urinary tract infections (UTIs), meningitis, ear infections, and eye infections. The brand name Gantanol is discontinued, but generic versions may be available.

What Is Silvadene?

Silvadene Cream 1% (silver sulfadiazine) is a topical (for the skin) antibiotic used to treat or prevent infections on areas of burned skin.

What Drugs Interact With Gantanol?

Gantanol may interact with:

Tell your doctor all medications and supplements you use.

What Drugs Interact With Silvadene?

Silvadene Cream may interact with cimetidine. Tell your doctor all medications you use. During pregnancy, Silvadene Cream should be used only when prescribed. It must not be used near the expected delivery date because of possible harm to the fetus. It is unknown if this medication passes into breast milk. Similar drugs pass into breast milk and may harm nursing infants who are ill, premature, less than 2 months old, or who have certain disorders (such as jaundice, high blood levels of bilirubin, G6PD deficiency). Breast-feeding while using this drug is not recommended in infants with these conditions. Consult your doctor before breast-feeding.

How Should Gantanol Be Taken?

To treat severe Infections the dose of Gantanol is 4 tablets (2 g) initially, followed by 2 tablets (1 g) three times daily thereafter.

How Should Silvadene Be Used?

Burn areas should be covered with Silvadene Cream 1% at all times. The cream should be applied once to twice daily to a thickness of approximately 1/16 inch. Whenever necessary, the cream should be reapplied to any areas where it has been removed by patient activity.
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