Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of AIDS dementia complex
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
AIDS dementia complex: A brain disorder in people with severe AIDS, causing loss of thinking capacity and affecting the ability to function. AIDS dementia complex is considered an AIDS-defining illness'that is, one of the serious illnesses that occurs in HIV-positive individuals warranting an AIDS diagnosis, according to the definition of AIDS by the Centers for Disease Control and Prevention (CDC).