Medical Information Only: This medication is not sold on this site. The information provided is for reference purposes only. Please consult your local physician or pharmacist for treatment.

Ceftix: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Ceftix - General Information

A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.

 

Pharmacology of Ceftix

Ceftix is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.

 

Ceftix for patients

 

Ceftix Interactions

Although the occurrence has not been reported with Cefizox, nephrotoxicity has been reported following concomitant administration of other cephalosporins and aminoglycosides.

 

Ceftix Contraindications

Cefizox (ceftizoxime for injection, USP) is contraindicated in patients who have known allergy to the drug.

 

Additional information about Ceftix

Ceftix Indication: For the treatment of infections due to susceptible strains of microorganisms. Mechanism Of Action: Ceftix is an aminothiazolyl cephalosporin with an extended spectrum of activity against many gram-negative, nosocomially acquired pathogens. It has excellent beta-lactamase stability, with good in vitro activity against Haemophilus influenzae, Neisseria gonorrhoeae and Klebsiella pneumoniae. Ceftix, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that ceftizoxime interferes with an autolysin inhibitor. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Ceftizoxime Synonyms: Ceftizoxima [inn-spanish]; Ceftizoximum [inn-latin] Drug Category: Cephalosporins; Anti-Bacterial Agents Drug Type: Small Molecule; Approved Other Brand Names containing Ceftizoxime: Cefizox; Cefizox in plastic container; Ceftix; Epocelin; Eposerin; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: 30% protein bound Biotransformation: Ceftizoxime is not metabolized, and is excreted virtually unchanged by the kidneys in 24 hours. Half Life: Not Available Dosage Forms of Ceftix: Solution Intravenous Tablet Rectal Chemical IUPAC Name: (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical Formula: C13H13N5O5S2 Ceftizoxime on Wikipedia: https://en.wikipedia.org/wiki/Ceftizoxime Organisms Affected: Enteric bacteria and other eubacteria