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Calmate R: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Calmate R - General Information

Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent. It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. It has several common applications such as brine for refrigeration plants, ice and dust control on roads, and in cement. It can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers. [Wikipedia]

 

Pharmacology of Calmate R

Calcium is the fifth most abundant element in the body and the major fraction is in the bony structure. Calcium plays important physiological roles, many of which are poorly understood. It is essential for the functional integrity of the nervous and muscular systems. It is necessary for normal cardiac function and is one of the factors that operates in the mechanisms involved in the coagulation of blood.

 

Calmate R for patients

 

WARNINGS

  • CAUTION: This solution must not be injected intramuscularly or subcutaneously.

10% Calcium Chloride Injection, USP is irritating to veins and must not be injected into tissues, since severe necrosis and sloughing may occur. Great care should be taken to avoid extravasation or accidental injection into perivascular tissues.

 

Calmate R Interactions

 

Calmate R Contraindications

Calcium chloride is contraindicated for cardiac resuscitation in the presence of ventricular fibrillation or in patients with the risk of existing digitalis toxicity.

 

Additional information about Calmate R

Calmate R Indication: For the treatment of hypocalcemia in those conditions requiring a prompt increase in blood plasma calcium levels, for the treatment of magnesium intoxication due to overdosage of magnesium sulfate, and used to combat the deleterious effects of hyperkalemia as measured by electrocardiographic (ECG), pending correction of the increased potassium level in the extracellular fluid. Mechanism Of Action: Calcium chloride in water dissociates to provide calcium (Ca2+) and chloride (Cl-) ions. They are normal constituents of the body fluids and are dependent on various physiological mechanisms for maintenance of balance between intake and output. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Calcium Chloride Synonyms: Anhydrous calcium chloride; CaCl2; Calcium chloride anhydrous; Calcium chloride dihydrate; Calcium chloride fused; Calcium chloride pellets; Calcium chloride solution; Calcium chloride, dihydrate; Calcium dichloride; Calcium Chloride Dihydrate BP; Chip calcium chloride; Liquid calcium chloride Drug Category: Supplements Drug Type: Small Molecule; Approved Other Brand Names containing Calcium Chloride: Bovikalc; Calcosan; Calmate R; Calol; Caloride; Calplus; Caltac; Calzina oral; Chrysoxel C 4; Daraccel; Dowflake; HSDB 923; Homberg's phosphorus; Huppert's reagent; Intergravin-orales; Jarcal; Liquical; Liquidow; Peladow; Snomelt; Stopit; Superflake anhydrous; Sure-step; U-Ramin MC; Unichem calchlor; Uramine MC; Absorption: Not Available Toxicity (Overdose): Too rapid injection may produce lowering of blood pressure and cardiac syncope. Persistent hypercalcemia from overdosage of calcium is unlikely because of rapid excretion. Protein Binding: Not Available Biotransformation: Approximately 80% of body calcium is excreted in the feces as insoluble salts; urinary excretion accounts for the remaining 20%. Half Life: Not Available Dosage Forms of Calmate R: Solution / drops Oral Solution Intravenous Liquid Intravenous Liquid Oral Chemical IUPAC Name: calcium dichloride Chemical Formula: CaCl2 Calcium Chloride on Wikipedia: https://en.wikipedia.org/wiki/Calcium_Chloride Organisms Affected: Humans and other mammals