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BZQ: Full Drug Profile
Medically reviewed by Min Clinic Staff | Updated: January 2026
BZQ - General Information
BZQ is an antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties. The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors.
Pharmacology of BZQ
BZQ is an antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties.
Additional information about BZQ
- BZQ Indication
Used to prevent and treat nausea and vomiting associated with anesthesia and surgery, administered intramuscularly or intravenously.
- Mechanism Of Action
- The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors.
- Generic Name
- Benzquinamide
- Drug Category
- Antiemetics; Antipsychotics
- Drug Type
- Small Molecule; Approved
- Other Brand Names containing Benzquinamide
- BZQ; Benzchinamide; Emete-con; Emeticon; Promecon; Quantril;
- Absorption
- Incomplete, with 33–39% bioavailability via the capsule and suppository routes, relative to the intramuscular route.
- Half Life
- 1-1.6 hours (for all formulations)
- Chemical IUPAC Name
- [3-(diethylcarbamoyl)-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl] acetate
- Chemical Formula
- C22H32N2O5
- Organisms Affected
- Humans and other mammals