Azolmen

Azolmen - General Information

Azolmen is an azole antifungal drug. [Wikipedia]

Pharmacology of Azolmen

Azolmen is a type of antifungal medicine known as an imidazole. It kills fungi and yeasts by interfering with their cell membranes.

Additional information about Azolmen

Azolmen Indication: Used for the treatment of various topical fungal infections, including athlete's foot (tinea pedis).
Mechanism Of Action: Azolmen works by inhibiting the production of a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol disrupts the cell membrane and causes holes to appear. The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. As bifonazole causes holes to appear in the cell membranes, essential constituents of the fungal cells can leak out. This kills the fungi.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Bifonazole
Synonyms: (+-)-1-(p,alpha-Diphenylbenzyl)imidazole; (+-)1-([1,1'-Biphenyl]-4-ylphenylmethyl)-1H-imidazole; 1-((4-Biphenylyl)phenylmethyl)-1H-imidazole; 1-(alpha-(4-Biphenylyl)benzyl)imidazole; 1-(p,alpha-Diphenylbenzyl)imidazole; Bifonazol [inn-spanish]; Bifonazolum [inn-latin]; Trifonazole; Bay h 4502
Drug Category: Antifungal Agents
Drug Type: Small Molecule; Approved

Other Brand Names containing Bifonazole: Amycor; Azolmen; Mycospor;
Absorption: Very low absorption following topical administration (0.6% of an applied dose). In cases of skin lesions absorption is increased (2.5%).
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Hepatic.
Half Life: 1-2 hours
Dosage Forms of Azolmen: Cream Topical
Chemical IUPAC Name: 1-[phenyl-(4-phenylphenyl)methyl]imidazole
Chemical Formula: C22H18N2
Bifonazole on Wikipedia: https://en.wikipedia.org/wiki/Bifonazole
Organisms Affected: Fungi