Arto-espasmol: Full Drug Profile

Arto-espasmol - General Information

A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia. Arto-espasmol is not approved for use in the U.S. or Canada, but is approved in various European countries.

Pharmacology of Arto-espasmol

Arto-espasmol is in a class of drugs called vasodilators. Arto-espasmol relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.

Additional information about Arto-espasmol

Arto-espasmol Indication

Used in the treatment of various blood vessel diseases (e.g., claudication, arteriosclerosis and Raynaud's disease) and nighttime leg cramps.

Mechanism Of Action

Arto-espasmol produces peripheral vasodilation by a direct effect on vascular smooth muscle.

Food Interactions

Take with food to reduce irritation.

Generic Name

Cyclandelate

Synonyms

Cyclandelic acid; Ciclandelato [inn-spanish]; Cyclandelatum [inn-latin]; 3,5,5-Trimethylcyclohexyl mandelate; 3,5,5-Trimethylcyclohexyl amygdalate; 3,3,5-Trimethylcyclohexyl mandelate

Drug Category

Vasodilator Agents

Drug Type

Small Molecule; Approved

Other Brand Names containing Cyclandelate

Arto-espasmol; Capilan; Ciclospasmol; Clandilon; Cyclergine; Cyclobral; Cyclolyt; Cyclomandol; Cyclospasmol; Dilatan; Natil; Novodil; Perebral; Saiclate; Sancyclan; Sepyron; Spasmione; Spasmocyclon; Spasmocyclone; Vasodyl;

Absorption

Well absorbed following oral administration.

Toxicity (Overdose)

Acute oral toxicity (LD50): 3950 mg/kg [Guinea pig]

Dosage Forms of Arto-espasmol

Tablet Oral

Chemical IUPAC Name

(3,3,5-trimethylcyclohexyl) 2-hydroxy-2-phenylacetate

Chemical Formula

C17H24O3

Organisms Affected

Humans and other mammals