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Acticin Cream: Full Drug Profile
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
Acticin Cream - General Information
A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Pharmacology of Acticin Cream
Acticin Cream, a pyrethroid, is active against a broad range of pests including lice, ticks, fleas, mites, and other arthropods.
Additional information about Acticin Cream
- Acticin Cream Indication
For the treatment of infestation with Sarcoptes scabiei (scabies).
- Mechanism Of Action
- Acticin Cream acts on the nerve cell membrane to disrupt the sodium channel current by which the polarization of the membrane is regulated. Delayed repolarization and paralysis of the pests are the consequences of this disturbance.
- Generic Name
- Permethrin
- Drug Category
- Enzyme Inhibitors; Insecticides
- Drug Type
- Small Molecule; Approved; Investigational
- Other Brand Names containing Permethrin
- PerFoam; Acticin Cream; Elimite; Elimite Cream; Nix; Nix Cream Rinse;
- Absorption
- Poorly absorbed through the skin.
- Toxicity (Overdose)
- Oral, rat LD50: 430 - 4000 mg/kg; skin, rabbit LD50: 2000 mg/kg.
- Biotransformation
- Rapidly metabolized by ester hydrolysis to inactive metabolites which are excreted primarily in the urine.
- Dosage Forms of Acticin Cream
- Cream Topical
- Chemical IUPAC Name
- [3-(phenoxy)phenyl]methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate
- Chemical Formula
- C21H20Cl2O3
- Permethrin on Wikipedia
- https://en.wikipedia.org/wiki/Permethrin
- Organisms Affected
- Scabies (Sarcoptes scabei) and other insects