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Zestoretic Side Effects Center

Medically reviewed by Min Clinic Staff | Updated: January 2026

Zestoretic (Lisinopril and Hydrochlorothiazide) side effects drug center

 

PROFESSIONAL

CONSUMER

SIDE EFFECTS

 

Zestoretic Side Effects Center

What Is Zestoretic?

Zestoretic (lisinopril and hydrochlorothiazide) is a combination of an angiotension converting enzyme (ACE) inhibitor and a diuretic used to treat high blood pressure (hypertension). Zestoretic is available in generic form.

What Are Side Effects of Zestoretic?

Common side effects of Zestoretic include:

  • dizziness (often on standing),
  • lightheadedness,
  • headache,
  • cough,
  • fatigue,
  • tired feeling,
  • depression,
  • blurred vision,
  • diarrhea,
  • constipation,
  • upset stomach,
  • skin rash, or
  • increased sweating.

Tell your doctor if you have any serious side effects of Zestoretic including: