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Xyrem: Detailed Datasheet

Medically reviewed by Min Clinic Staff | Updated: January 2026
  • Generic Name: sodium oxybate
  • Brand Name: Xyrem

side effects drug center xyrem (sodium oxybate) drug - patient side effects and images

 

PROFESSIONAL

CONSUMER

SIDE EFFECTS

Xyrem Patient Information Including Side Effects

Brand Names: Xyrem

Generic Name: sodium oxybate

What is sodium oxybate (Xyrem)?

Sodium oxybate is a central nervous system depressant. It is used to treat cataplexy (sudden loss of muscle strength) and reduce daytime sleepiness caused by narcolepsy in adults and children at least 7 years old.

Sodium oxybate is also known as GHB, a known street drug of abuse. Because of the potential for abuse and serious side effects, sodium oxybate is available only from a certified pharmacy under a special program. Your doctor must be registered in the program in order to prescribe sodium oxybate for you.

Sodium oxybate may also be used for purposes not listed in this medication guide.

What are the possible side effects of sodium oxybate (Xyrem)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • weak or shallow breathing, breathing that stops for short periods of time;