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Increlex: Detailed Datasheet

Medically reviewed by Min Clinic Staff | Updated: January 2026

side effects drug center increlex (mecasermin [rdna origin] injection) drug - patient side effects and images

 

PROFESSIONAL

CONSUMER

SIDE EFFECTS

Increlex Patient Information Including Side Effects

Brand Names: Increlex

Generic Name: mecasermin

What is mecasermin (Increlex)?

Mecasermin is a man-made form of insulin-like growth factor-1 (IGF-1), a substance that is normally produced in the body. IGF-1 is important for the growth of bones and muscles.

Mecasermin is used to treat growth failure in children whose bodies do not make enough IGF-1.

Mecasermin is not for use in children who have growth hormone deficiency, malnutrition, underactive thyroid, or those who are taking long-term steroid medications.

Mecasermin may also be used for purposes not listed in this medication guide.

What are the possible side effects of mecasermin (Increlex)?

Get emergency medical help if your child has signs of an allergic reaction: hives; difficult breathing; swelling of your child's face, lips, tongue, or throat.

Call your doctor at once if your child has:

  • pain in the hip or knee, walking with a limp;
  • low blood sugar--headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery;
  • swollen tonsils--snoring, breathing problems during sleep, pain or fullness in the ear, hearing problems; or
  • increased pressure inside the skull--headache with vision problems, nausea, pain behind the eyes.

Common side effects may include:

  • low blood sugar;