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Neutrexin Side Effects Center

Medically reviewed by Min Clinic Staff | Updated: January 2026
  • Generic Name: trimetrexate glucuronate inj
  • Brand Name: Neutrexin

Neutrexin (Trimetrexate Glucuronate Inj) side effects drug center

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CONSUMER

SIDE EFFECTS

Neutrexin Side Effects Center

What Is Neutrexin?

Neutrexin (trimetrexate glucuronate) for Injection is an inhibitor of the enzyme dihydrofolate reductase (DHFR) used along with leucovorin as an alternative therapy for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients, including patients with the acquired immune deficiency syndrome (AIDS), who are intolerant of, or are refractory to, trimethoprim-sulfamethoxazole therapy or for whom trimethoprim-sulfamethoxazole is contraindicated. The brand name Neutrexin is discontinued, but generic versions may be available. Common side effects of Neutrexin (trimetrexate glucuronate) include:

  • fever
  • nausea
  • fatigue
  • rash and itching
  • nausea