Monovisc

Monovisc (high molecular weight hyaluronan injection) is a complex sugar used to treat pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy or simple analgesics (e.g., acetaminophen). Common side effects of Monovisc include:

• joint pain and swelling,
• injection site reactions,
• rash,
• headache,
• dizziness,
• chills,
• hives,
• itching,
• nausea,
• muscle cramps
,
• swelling of legs and feet, and
• a general feeling of being unwell (malaise)

Monovisc is supplied in a single-use 5 mL syringe containing a 4 mL dose of treatment. Monovisc may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, Monovisc should only be administered if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Monovisc (high molecular weight hyaluronan injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

 

Monovisc Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• bleeding;
• increased knee pain; or
• signs of infection (warmth, swelling, redness) around your knee.

Common side effects may include:

• joint pain, stiffness, or swelling;
• itching, numbness, or tingling;
• headache, dizziness;
• back pain;
• swelling, pain, redness, or mild discomfort where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Monovisc (High Molecular Weight Hyaluronan Injection)

 

Monovisc Professional Information

SIDE EFFECTS

Potential Adverse Effects Of The Device On Health

Reported Device-Related Adverse Events

The most common reported adverse events associated with Monovisc™ are the following:

• Arthralgia
• Joint swelling
• Injection site pain

Incidences of rash, headache, dizziness, chills, hives, itching, nausea, muscle cramps, peripheral edema, and malaise have also been reported in association with intra-articular injections.

A complete listing of the frequency and rate of adverse events identified in the clinical studies is provided in the Safety section.

Read the entire FDA prescribing information for Monovisc (High Molecular Weight Hyaluronan Injection)