Lorcet
- Generic Name: hydrocodone bitartrate and acetaminophen tablet
- Brand Name: Lorcet
Lorcet (Hydrocodone Bitartrate and Acetaminophen Tablet) side effects drug center
Lorcet Side Effects Center
What Is Lorcet?
Lorcet (hydrocodone bitartrate and acetaminophen) is a combination of an opioid analgesic (pain reliever)/antitussive (anticough), and a non-salicylate analgesic and anti-fever drug indicated for the relief of moderate to severe pain.
What Are Side Effects of Lorcet?
Side effects of Lorcet include:
- nausea,
- vomiting,
- upset stomach,
- constipation,
- lightheadedness,
- dizziness,
- drowsiness,
- anxiety,
- headache,
- blurred vision,
- ringing in your ears, or
- dry mouth.
Serious side effects of Lorcet include:
- mental/mood changes,
- confusion,
- fear,
- unusual thoughts or behavior,
- severe stomach or abdominal pain,
- lightheadedness,
- clay-colored stools,
- yellowing of the skin or eyes, and
- difficulty urinating.
Rare, but serious side effects of Lorcet include:
- fainting,
- seizure (convulsions),
- slow or shallow breathing,
- unusual drowsiness, or
- difficulty waking up.
There is a risk of addiction to Lorcet.
Dosage for Lorcet
Dosage of Lorcet should be adjusted according to the severity of the pain and the response of the patient. Tolerance to hydrocodone can develop with continued use and that the incidence of untoward effects is dose related. The usual adult dosage of Lorcet is one tablet every four to six hours as needed for pain. The total daily dosage of Lorcet should not exceed 6 tablets.
What Drugs, Substances, or Supplements Interact with Lorcet?
Many other medications may interact with Lorcet, especially other drugs that cause drowsiness (other narcotics, benzodiazapines, sleep medications, or cold and allergy medications). Tell your doctor all medications and supplements you use.
Lorcet During Pregnancy or Breastfeeding
Tell you doctor if you are pregnant or plan to become pregnant while taking of Lorcet; it may slightly increase the risk of birth defects if used during the first two months of pregnancy. Lorcet can pass into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding. Withdrawal symptoms may occur if you suddenly stop using Lorcet.
Additional Information
Our Lorcet (hydrocodone bitartrate and acetaminophen) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
Lorcet Consumer Information
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.
Call your doctor at once if you have:
- noisy breathing, sighing, shallow breathing, breathing that stops;
- a light-headed feeling, like you might pass out;
- liver problems--nausea, upper stomach pain, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- low cortisol levels-- nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness; o
- high levels of serotonin in the body--agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea.
Serious breathing problems may be more likely in older adults and in those who are debilitated or have wasting syndrome or chronic breathing disorders.
Common side effects include:
- dizziness, drowsiness, feeling tired;
- nausea, vomiting, stomach pain;
- constipation; or
- headache.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Lorcet (Hydrocodone Bitartrate and Acetaminophen Tablet)
Lorcet Professional Information
SIDE EFFECTS
The most frequently reported adverse reactions include lightheadedness, dizziness, sedation, nausea and vomiting. These effects seem to be more prominent in ambulatory than in non-ambulatory patients and some of these adverse reactions may be alleviated if the patient lies down.
Other adverse reactions include:
Central Nervous System
Drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, psychic dependence, mood changes.
Gastrointestinal System
Prolonged administration of Lorcet® 10/650 may produce constipation.
Genitourinary System
Ureteral spasm, spasm of vesical sphincters and urinary retention have been reported with opiates.
Respiratory Depression
Hydrocodone bitartrate may produce dose-related respiratory depression by acting directly on the brain stem respiratory centers. (see OVERDOSAGE).
Special Senses
Cases of hearing impairment or permanent loss have been reported predominantly in patients with chronic overdose.
Dermatological: Skin rash, pruritus.
The following adverse drug events may be borne in mind as potential effects of acetaminophen: allergic reactions, rash, thrombocytopenia, agranulocytosis. Potential effects of high dosage are listed in the OVERDOSAGE section.
Drug Abuse And Dependence
Misuse, Abuse, and Diversion of Opioids
Lorcet® 10/650 tablets contain hydrocodone, an opioid agonist, and are a Schedule III controlled substance. Lorcet® 10/650, and other opioids used in analgesia can be abused and are subject to criminal diversion.
Addiction is a primary, chronic, neurobiologic disease, with genetic, psychosocial, and environmental factors influencing its development and manifestations. It is characterized by behaviors that include one or more of the following: impaired control over drug use, compulsive use, continued use despite harm, and craving. Drug addiction is a treatable disease utilizing a multidisciplinary approach, but relapse is common.
“Drug seeking” behavior is very common in addicts and drug abusers. Drug-seeking tactics include emergency calls or visits near the end of office hours, refusal to undergo appropriate examination, testing or referral, repeated “loss” of prescriptions, tampering with prescriptions and reluctance to provide prior medical records or contact information for other treating physician (s). “Doctor shopping” to obtain additional prescriptions is common among drug abusers and people suffering from untreated addiction.
Abuse and addiction are separate and distinct from physical dependence and tolerance. Physical dependence usually assumes clinically significant dimensions only after several weeks of continued opioid use, although a mild degree of physical dependence may develop after a few days of opioid therapy. Tolerance, in which increasingly large doses are required in order to produce the same degree of analgesia, is manifested initially by a shortened duration of analgesic effect, and subsequently by decreases in the intensity of analgesia. The rate of development of tolerance varies among patients. Physicians should be aware that abuse of opioids can occur in the absence of true addiction and is characterized by misuse for non-medical purposes, often in combination with other psychoactive substances. Lorcet® 10/650, like other opioids, may be diverted for non-medical use. Record-keeping of prescribing information, including quantity, frequency, and renewal requests is strongly advised.
Proper assessment of the patient, proper prescribing practices, periodic reevaluation of therapy, and proper dispensing and storage are appropriate measures that help to limit abuse of opioid drugs.
Read the entire FDA prescribing information for Lorcet (Hydrocodone Bitartrate and Acetaminophen Tablet)
&Copy; Lorcet Patient Information is supplied by Cerner Multum, Inc. and Lorcet Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.