Arthrotec vs. Voltaren

• Are Arthrotec and Voltaren the Same Thing?
• What Are Possible Side Effects of Arthrotec?
• What Are Possible Side Effects of Voltaren?
• What Is Arthrotec?
• What Is Voltaren?
• What Drugs Interact with Arthrotec?
• What Drugs Interact with Voltaren?
• How Should Arthrotec Be Taken?
• How Should Voltaren Be Taken?

Arthrotec (diclofenac sodium/misoprostol) and Voltaren (diclofenac) are used to treat osteoarthritis and rheumatoid arthritis

Arthrotec is used in people at high risk for developing stomach or intestinal ulcers.

Voltaren is also used to treat ankylosing spondylitis.

Arthrotec and Voltaren both contain a nonsteroidal anti-inflammatory drug (NSAID) and Arthrotec also contains a prostaglandin that protects the stomach from irritating effects of NSAIDs.

The brand name Voltaren is no longer available in the U.S. Generic versions may be available.

Side effects of Arthrotec and Voltaren that are similar include diarrhea, upset stomach or stomach pain, bloating, gas, dizziness, headache, blurred vision, or ringing in your ears.

Side effects of Arthrotec that are different from Voltaren include nausea, drowsiness, or unusual vaginal bleeding.

Side effects of Voltaren that are different from Arthrotec include heartburn, constipation, ulcers, nervousness, or skin itching or rash.

Common side effects of Arthrotec include:

• nausea,
• bloating,
• gas,
• dizziness,
• drowsiness,
• headache,
• blurred vision,
• ringing in your ears, or
• unusual vaginal bleeding.

Tell your doctor if you have serious side effects of Arthrotec including:

• difficult or painful swallowing,
• swelling of the hands or feet,
• sudden or unexplained weight gain,
• vision changes,
• mental/mood changes (e.g., depression),
• fast or pounding heartbeat,
• persistent or severe headache,
• fainting,
• menstrual problems/irregular periods,
• unusual tiredness,
• easy bruising or bleeding,
• signs of infection (e.g., fever, persistent sore throat),
• changes in the amount of urine, or
• unexplained stiff neck.

Common side effects of Voltaren include:

• nausea,
• stomach pain,
• upset stomach,
• diarrhea,
• gas,
• ulcers, or
• itching,
• dryness,
• redness,
• scaling,
• numbness and tingling,
• cysts,
• pimples, or other
• skin irritation where the medicine was applied.

Arthrotec (diclofenac sodium/misoprostol) is a combination non-steroidal anti-inflammatory drug (NSAID) and a prostaglandin that protects the stomach from irritating effects of NSAIDs used to treat osteoarthritis and rheumatoid arthritis in people at high risk for developing stomach or intestinal ulcers. Arthrotec is available in generic form. Common side effects of Arthrotec include diarrhea and upset stomach or stomach pain within a few weeks after you start taking this medication, and usually last for about 1 week.

Voltaren Gel (diclofenac sodium topical gel) is a topical gel nonsteroidal anti-inflammatory drug (NSAID) used to treat pain of osteoarthritis of joints that are amenable to topical treatment, such the hands and knees.

Arthrotec may interact with blood thinners, cyclosporine, digoxin, diuretics (water pills), insulin or oral diabetes medicine, lithium, methotrexate, phenobarbital, steroids, aspirin or other NSAIDs, or ACE inhibitors. Tell your doctor all medications you use. Arthrotec must not be used during pregnancy. It can harm the fetus and mother. Use birth control while taking this medication. This medication passes into breast milk. However, this drug is unlikely to harm a nursing infant. Consult your doctor before breastfeeding.

Voltaren Gel may interact with aspirin, lithium, diuretics (water pills), blood thinners, and methotrexate.

Voltaren Gel may also interact with heart or blood pressure medications, cyclosporine, steroids, certain antibiotics, and other topical treatments.

For the relief of rheumatoid arthritis and osteoarthritis, the recommended dose of Arthrotec is 50 mg diclofenac sodium/200 mcg misoprostol or 75 mg diclofenac sodium/200 mcg misoprostol.

The proper amount of Voltaren® Gel should be measured using the dosing card supplied in the drug product carton. The dosing card is made of clear polypropylene. The dosing card should be used for each application of drug product. The gel should be applied within the rectangular area of the dosing card up to the 2 gram or 4 gram line (2 g for each elbow, wrist, or hand, and 4 g for each knee, ankle, or foot). The 2 g line is 2.25 inches long. The 4 g line is 4.5 inches long. The dosing card containing Voltaren® Gel can be used to apply the gel. The hands should then be used to gently rub the gel into the skin. After using the dosing card, hold with fingertips, rinse, and dry. If treatment site is the hands, patients should wait at least one (1) hour to wash their hands.

Lower Extremities, Including The Feet, Ankles, Or Knees

Apply the gel (4 g) to the affected foot, ankle, or knee 4 times daily. Voltaren® Gel should be gently massaged into the skin ensuring application to the entire affected foot, or knee or ankle. The entire foot includes the sole, top of the foot and the toes. Do not apply more than 16 g daily to any single joint of the lower extremities.

Upper Extremities Including The Hands, Wrists, Or Elbows

Apply the gel (2 g) to the affected hand, wrist, or elbow 4 times daily. Voltaren® Gel should be gently massaged into the skin ensuring application to the entire affected hand, wrist, or elbow. The entire hand includes the palm, back of the hands, and the fingers. Do not apply more than 8 g daily to any single joint of the upper extremities.

Total dose should not exceed 32 g per day, over all affected joints.

Special Precautions

• Avoid showering/bathing for at least 1 hour after the application. Inform patient to wash his/her hands after use, unless the hands are the treated joint. If Voltaren® Gel is applied to the hand (s) for treatment; inform patient not to wash the treated hand (s) for at least 1 hour after the application.
• Do not apply Voltaren® Gel to open wounds.
• Avoid contact of Voltaren® Gel with eyes and mucous membranes.
• Do not apply external heat and/or occlusive dressings to treated joints.
• Avoid exposure of the treated joint(s) to natural or artificial sunlight.
• Avoid concomitant use of Voltaren® Gel on the treated skin site with other topical products, including sunscreens, cosmetics, lotions, moisturizers, insect repellants, or other topical medications
• Concomitant use of Voltaren® Gel with oral non-steroidal anti-inflammatory drugs(NSAIDs) has not been evaluated, and may increase adverse NSAIDs effects. Do not use combination therapy with Voltaren® Gel and an oral NSAID unless the benefit outweighs the risk and conduct periodic laboratory evaluations.
• Avoid wearing of clothing or gloves for at least 10 minutes after applying Voltaren® Gel.